Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI Guidelines—2024–2025 Revision: Part I—Guidelines on Intranasal Treatments

Title (eng)
Allergic Rhinitis and Its Impact on Asthma (ARIA)-EAACI Guidelines—2024–2025 Revision: Part I—Guidelines on Intranasal Treatments
Author
Bernardo Sousa‐Pinto
MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal
Author
Jean Bousquet
Institute of Allergology Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt‐Universität Zu Berlin Berlin Germany
Author
Rafael José Vieira
MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal
Author
Holger J. Schünemann
Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology Berlin Germany
Author
Torsten Zuberbier
Institute of Allergology Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt‐Universität Zu Berlin Berlin Germany
Author
Antonio Bognanni
Department of Health Research Methods, Evidence, and Impact & Department of Medicine McMaster University Hamilton Ontario Canada
Author
Alkis Togias
Division of Allergy, Immunology, and Transplantation (DAIT) National Institute of Allergy and Infectious Diseases, NIH Bethesda Maryland USA
Author
Boleslaw Samolinski
Department of Prevention of Environmental Hazards, Allergology and Immunology Medical University of Warsaw Warsaw Poland
Author
Arunas Valiulis
Institute of Clinical Medicine and Institute of Health Sciences Medical Faculty of Vilnius University Vilnius Lithuania
Author
Sian Williams
International Primary Care Respiratory Group IPCRG Edinburgh UK
Author
Anna Bedbrook
ARIA (Allergic Rhinitis and Its Impact on Asthma) Montpellier France
Author
Wienczyslawa Czarlewski
ARIA (Allergic Rhinitis and Its Impact on Asthma) Montpellier France
Author
Maria Jose Torres
Allergy Unit Málaga Regional University Hospital of Málaga, Malaga University, ARADyAL Malaga Spain
Author
Mohamed H. Shamji
Immunomodulation and Tolerance Group and Allergy and Clinical Immunology Imperial College London London UK
Author
Mário Morais‐Almeida
Allergy Center CUF Descobertas Hospital Lisbon Portugal
Author
G. Walter Canonica
Department of Biomedical Science Humanitas University, Pieve Emanuele Milan Italy
Author
Leticia de las Vecillas
Department of Allergy Hospital La Paz Institute for Health Research (IdiPAZ) Madrid Spain
Author
Mark S. Dykewicz
Section of Allergy and Immunology Saint Louis University School of Medicine Saint Louis Missouri USA
Author
Cristina Jacomelli
“Respiriamo Insieme” Association, Asthma & Allergy Center Padova Italy
Author
Ludger Klimek
Department of Otolaryngology, Head & Neck Surgery Universitätsmedizin Mainz Mainz Germany
Author
Lucas Leemann
Department of Political Science University of Zürich Zürich Switzerland
Author
Olga Lourenço
RISE‐Health, Department of Medical Sciences Faculty of Health Sciences, University of Beira Interior Covilhã Portugal
Author
Yuliia Palamarchuk
Finnish Meteorological Institute (FMI) Atmospheric Composition Research Helsinki Finland
Author
Nikolaos G. Papadopoulos
Allergy Department 2nd Pediatric Clinic, University of Athens Athens Greece
Author
Ana Margarida Pereira
MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal
Author
Marine Savouré
Barcelona Institute for Global Health (ISGlobal) Barcelona Spain
Author
Sanna K. Toppila‐Salmi
Department of Allergy, Skin and Allergy Hospital, Inflammation Center Helsinki University Hospital and University of Helsinki Helsinki Finland
Author
Maria Teresa Ventura
University of Bari Medical School Bari Italy
Author
Juan José Yepes‐Nuñez
School of Medicine Universidad de los Andes Bogotá D. C. Colombia
Author
Alvaro A. Cruz
Fundacao ProAR and (Faculdade de Medicina da) Universidade Federal da Bahia Salvador Bahia Brazil
Author
Giorgio Ciprandi
Casa di Cura Villa Montallegro Allergology Department Genova Italy
Author
Bilun Gemicioglu
Department of Pulmonary Diseases and Institute of Pulmonology and Tuberculosis Istanbul University‐Cerrahpaşa, Cerrahpaşa Faculty of Medicine Istanbul Turkey
Author
Mattia Giovannini
Department of Health Sciences University of Florence Florence Italy
Author
Brigita Gradauskiene
Department of Immunology and Allergology Lithuanian University of Health Sciences Kaunas Lithuania
Author
Tuomas Jartti
Department of Pediatrics and Adolescent Medicine University of Turku, Turku University Hospital Turku Finland
Author
Miloš Jeseňák
Institute of Clinical Immunology and Medical Genetics, Department of Paediatrics and Adolescent Medicine, Department of Pulmonology and Phthisiology Jessenius Faculty of Medicine Martin Slovakia
Author
Piotr Kuna
Division of Internal Medicine, Asthma and Allergy Barlicki University Hospital, Medical University of Lodz Lodz Poland
Author
Violeta Kvedariene
Institute of Clinical Medicine, Clinic of Chest Diseases and Allergology, Faculty of Medicine Vilnius University Vilnius Lithuania
Author
Désirée E. Larenas‐Linnemann
Center of Excellence in Asthma and Allergy Médica Sur Clinical Foundation and Hospital México City Mexico
Author
Amir HA Latiff
Allergy & Immunology Centre Pantai Hospital Kuala Lumpur Kuala Lumpur Malaysia
Author
Yousser Mohammad
National Center for Research in Chronic Respiratory Diseases, Collaborating With WHO—EMRO Tishreen University School of Medicine Latakia Syria
Author
Ken Ohta
Japan Antituberculosis Association (JATA) Fukujuji Hospital Tokyo Japan
Author
Padukudru A. Mahesh
Department of Respiratory Medicine JSS Medical College, JSSAHER Mysuru Mysore Karnataka India
Author
Isabella Pali‐Schöll
Departement of Biological Sciences and Pathophysiology, University of Veterinary Medicine, Vienna, Austria
Author
Oliver Pfaar
Section of Rhinology and Allergy, Department of Otorhinolaryngology, Head and Neck Surgery University Hospital Marburg, Philipps‐Universität Marburg Marburg Germany
Author
Frederico S. Regateiro
Allergy and Clinical Immunology Department Hospitais da Universidade de Coimbra, Unidade Local de Saúde de Coimbra Coimbra Portugal
Author
Nicolas Roche
Pneumologie AP‐HP Centre Université de Paris Cité, Hôpital Cochin Paris France
Author
Luís Taborda‐Barata
UBIAir—Clinical & Experimental Lung Centre and CICS‐UBI Health Sciences Research Centre University of Beira Interior Covilhã Portugal
Author
Charlotte Suppli Ulrik
Department of Respiratory Medicine Copenhagen University Hospital‐Hvidovre Copenhagen Denmark
Author
Marylin Valentin Rostan
Pediatrics, Allergy & Immunology, Latín American Society of Allergy Asthma & Immunology (SLAAi) Montevideo Uruguay
Author
Giovanni Viegi
Pulmonary Environmental Epidemiology Unit CNR Institute of Clinical Physiology Pisa Italy
Author
Luo Zhang
Department of Otolaryngology, Head and Neck Surgery Beijing TongRen Hospital and Beijing Institute of Otolaryngology Beijing China
Author
Tari Haahtela
Skin and Allergy Hospital Helsinki University Hospital, and University of Helsinki Helsinki Finland
Author
Ivan Cherrez‐Ojeda
Universidad Espíritu Santo Samborondón Ecuador
Author
Juan Carlos Ivancevich
Servicio de Alergia e Immunologia Clinica Santa Isabel Buenos Aires Argentina
Author
Nikolai Khaltaev
Global NCD Platform Geneva Switzerland
Author
Arzu Yorgancioglu
Department of Pulmonary Diseases Celal Bayar University, Faculty of Medicine Manisa Turkey
Author
Baharudin Abdullah
Department of Otorhinolaryngology—Head and Neck Surgery, School of Medical Sciences Universiti Sains Malaysia Kubang Kerian Kelantan Malaysia
Author
Mona Al‐Ahmad
Microbiology Department College of Medicine, Kuwait University Kuwait City Kuwait
Author
Maryam Ali Al‐Nesf
Adult Allergy and Immunology Division—Hamad Medical Corporation Doha Qatar
Author
Rita Amaral
MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal
Author
Julijana Asllani
Department of Internal Medicine University of Medicine Tirana Albania
Author
Karl‐C Bergmann
Institute of Allergology Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt‐Universität Zu Berlin Berlin Germany
Author
Jonathan A. Bernstein
Division of Immunology, Allergy and Rheumatology, Department of Medicine University of Cincinnati College of Medicine Cincinnati Ohio USA
Author
Michael S. Blaiss
Department of Pediatrics Medical College of Georgia at Augusta University Augusta Georgia USA
Author
Fulvio Braido
Department of Internal Medicine (DIMI) University of Genoa Genoa Italy
Author
Paulo Camargos
Department of Pediatrics, Medical School Federal University of Minas Gerais Belo Horizonte Brazil
Author
Pedro Carreiro‐Martins
NOVA Medical School/Comprehensive Health Research Centre (CHRC) Lisbon Portugal
Author
Thomas Casale
Division of Allergy/Immunology University of South Florida Tampa Florida USA
Author
Lorenzo Cecchi
SOS Allergology and Clinical Immunology USL Toscana Centro Prato Italy
Author
Alessandro Fiocchi
Allergy, Bambino Gesù Children's Hospital Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Rome Italy
Author
Antonio F. M. Giuliano
Department of Internal Medicine ‘A. Murri’ and Unit of Geriatric Immunoallergology University of Bari Medical School Bari Italy
Author
George Christoff
Faculty of Public Health Sofia Medical University Sofia Bulgaria
Author
Ieva Cirule
Latvian Association of Allergists University Children Hospital Riga Latvia
Author
Jaime Correia de Sousa
Life and Health Sciences Research Institute (ICVS), School of Medicine University of Minho Braga Portugal
Author
Elisio M. Costa
CINTESIS@RISE, Biochemistry Lab, Faculty of Pharmacy and Competence Center on Active and Healthy Ageing University of Porto Porto Portugal
Author
Stefano Del Giacco
Department of Medical Sciences and Public Health and Unit of Allergy and Clinical Immunology University Hospital “Duilio Casula”, University of Cagliari Cagliari Italy
Author
Philippe Devillier
VIM Suresnes, UMR 0892, Pôle Des Maladies Des Voies Respiratoires, Hôpital Foch Université Paris‐Saclay Suresnes France
Author
Dejan Dokic
Medical Faculty Skopje University Clinic of Pulmology and Allergy Skopje Republic of North Macedonia
Author
Elham Hossny
Pediatric Allergy, Immunology and Rheumatology Unit Children's Hospital, Ain Shams University Cairo Egypt
Author
Tomohisa Iinuma
Department of Otorhinolaryngology Chiba University Chiba Japan
Author
Carla Irani
Department of Internal Medicine and Infectious Diseases St Joseph University, Hotel Dieu de France Hospital Beirut Lebanon
Author
Zhanat Ispayeva
Department of Allergology and Clinical Immunology, Kazakhstan Association of Allergology and Clinical Immunology Kazakh National Medical University Almaty Kazakhstan
Author
Kaja Julge
Institute of Clinical Medicine Children's Clinic, Tartu University Tartu Estonia
Author
Igor Kaidashev
Poltava State Medical University Immunology & Allergology Department Poltava Ukraine
Author
Kazi S. Bennoor
Department of Respiratory Medicine National Institute of Diseases of the Chest and Hospital Dhaka Bangladesh
Author
Helga Kraxner
Department of Otorhinolaryngology, Head and Neck Surgery Semmelweis University Budapest Hungary
Author
Inger Kull
Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet Stockholm Sweden
Author
Marek Kulus
Department of Pediatric Respiratory Diseases and Allergology Medical University of Warsaw Warsaw Poland
Author
Maciej Kupczyk
Division of Internal Medicine, Asthma and Allergy Barlicki University Hospital, Medical University of Lodz Lodz Poland
Author
Andriy Kurchenko
Department of Clinical and Laboratory Immunology, Allergology and Medical Genetics Bogomolets National Medical University Kyiv Ukraine
Author
Stefania La Grutta
Institute of Translational Pharmacology (IFT)‐National Research Council (CNR) Palermo Italy
Author
Neven Miculinic
Croatian Pulmonary Society Clinical Center for Pulmonary Diseases Zagreb Croatia
Author
Lan Le Thi Tuyet
Asthma, COPD Outpatient Care Unit University Medical Center Hô‐Chi‐Minh City Vietnam
Author
Michael Makris
Allergy Unit “D Kalogeromitros”, 2nd Department of Dermatology and Venereology, National & Kapodistrian University of Athens “Attikon” University Hospital Athens Greece
Author
Branislava Milenkovic
Clinic for Pulmonary Diseases, Clinical Center of Serbia, Faculty of Medicine University of Belgrade, Serbian Association for Asthma and COPD Belgrade Serbia
Author
Sang Min Lee
Division of Respiratory Disease and Allergy, Department of Internal Medicine Dankook University College of Medicine Cheonan Republic of Korea
Author
Stephen Montefort
Department of Medicine, Faculty of Medicine and Surgery University of Malta Msida Malta
Author
Andre Moreira
EPIUnit‐Institute of Public Health University of Porto, and Laboratory for Integrative and Translational Research in Population Health (ITR) Porto Portugal
Author
Joaquim Mullol
Rhinology Unit & Smell Clinic, ENT Department Hospital Clínic Barcelona Spain
Author
Rachel Nadif
Inserm Equipe D'epidémiologie Respiratoire Intégrative, CESP Villejuif France
Author
Alla Nakonechna
Imperial College Healthcare NHS Trust London UK
Author
Hugo E. Neffen
Center of Allergy, Immunology and Respiratory Diseases Santa Fe Argentina
Author
Marek Niedoszytko
Department of Allergology Medical University of Gdansk Gdansk Poland
Author
Dieudonné Nyembue
ENT Department University Hospital of Kinshasa Kinshasa Democratic Republic of the Congo
Author
Robyn E. O'Hehir
Allergy, Asthma and Clinical Immunology, Alfred Health and Department of Immunology, Central Clinical School Monash University Melbourne Victoria Australia
Author
Ismail Ogulur
Swiss Institute of Allergy and Asthma Research (SIAF) University of Zurich Davos Switzerland
Author
Yoshitaka Okamoto
Chiba Rosai Hospital ENT Department Chiba Japan
Author
Heidi Olze
Department of Otorhinolaryngology Charité—Universitätsmedizin Berlin Berlin Germany
Author
Oscar Palomares
Department of Biochemistry and Molecular Biology, School of Chemistry Complutense University of Madrid Madrid Spain
Author
Petr Panzner
Department of Immunology and Allergology, Faculty of Medicine in Pilsen Charles University Prague Czech Republic
Author
Vincenzo Patella
Division of Allergy and Clinical Immunology Department of Medicine, “Santa Maria della Speranza” Hospital, Battipaglia Salerno Italy
Author
Ruby Pawankar
Department of Pediatrics Nippon Medical School Tokyo Japan
Author
Constantinos Pitsios
Medical School University of Cyprus Nicosia Cyprus
Author
Todor A. Popov
Clinic of Occupational Diseases University Hospital Sveti Ivan Rilski Sofia Bulgaria
Author
Francesca Puggioni
IRCCS Humanitas Research Center Personalized Medicine Asthma & Allergy, Rozzano Milan Italy
Author
Santiago Quirce
Department of Allergy Hospital La Paz Institute for Health Research (IdiPAZ) Madrid Spain
Author
Agné Ramonaité
Department of Pulmonology and Allergology Klaipeda National Hospital Klaipėda Lithuania
Author
Marysia Recto
Division of Adult and Pediatric Allergy and Immunology University of the Philippines—Philippines General Hospital Manila Philippines
Author
Maria Susana Repka‐Ramirez
Department of Allergy Clinics Hospital, National University San Lorenzo Paraguay
Author
Graham Roberts
Faculty of Medicine University of Southampton Southampton UK
Author
Karla Robles‐Velasco
Universidad Espíritu Santo Samborondón Ecuador
Author
Menachem Rottem
Division of Allergy, Asthma and Clinical Immunology Emek Medical Center Afula Israel
Author
Marianella Salapatas
Aria Asthma, Rhinitis, Immunology & Allergy Department Athens Greece
Author
Joaquin Sastre
Allergy Service, Fundacion Jimenez Diaz Autonoma University of Madrid, CIBERES‐ISCIII Madrid Spain
Author
Nicola Scichilone
PROMISE Department University of Palermo Palermo Italy
Author
Juan‐Carlos Sisul
Allergy & Asthma Medical Director, CLINICA SISUL, FACAAI, SPAAI Asuncion Paraguay
Author
Dirceu Solé
Division of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics Federal University of São Paulo São Paulo Brazil
Author
Manuel E. Soto‐Martinez
Division of Respiratory Medicine, Department of Pediatrics Hospital Nacional de Niños, Universidad de Costa Rica San Jose Costa Rica
Author
Milan Sova
Department of Respiratory Medicine and Tuberculosis University Hospital Brno Czech Republic
Author
Pongsakorn Tantilipikorn
Department of Otolaryngology, Faculty of Medicine Siriraj Hospital Mahidol University Bangkok Thailand
Author
Ana Todo‐Bom
Imunoalergologia, Centro Hospitalar Universitário de Coimbra, Faculty of Medicine University of Coimbra Coimbra Portugal
Author
Vladyslav Tsaryk
Department of Clinical and Laboratory Immunology, Allergology and Medical Genetics Bogomolets National Medical University Kyiv Ukraine
Author
Ioanna Tsiligianni
International Primary Care Respiratory Group IPCRG Aberdeen UK
Author
Marilyn Urrutia‐Pereira
Federal University of Pampa Department of Medicine Uruguaiana Brazil
Author
Erkka Valovirta
Department of Lung Diseases and Clinical Immunology University of Turku Turku Finland
Author
Tuula Vasankari
FiLHA Finnish Lung Health Association Helsinki Finland
Author
Dana Wallace
Nova Southeastern University College of Allopathic Medicine Fort Lauderdale Florida USA
Author
De Yun Wang
Department of Otolaryngology Yong Loo Lin School of Medicine, National University of Singapore Singapore Republic of Singapore
Author
Margitta Worm
Division of Allergy and Immunology, Department of Dermatology, Allergy and Venerology Charité Universitätsmedizin Berlin Berlin Germany
Author
Osman M. Yusuf
The Allergy and Asthma Institute Allergy & Asthma Department Islamabad Pakistan
Author
Mihaela Zidarn
University Clinic of Respiratory and Allergic Diseases Pulmonary & Allergy Department Golnik Slovenia
Author
Sara Gil‐Mata
MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal
Author
Manuel Marques‐Cruz
MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal
Author
Bassam Mahboub
Pulmonary Department Rashid Hospital, DUBAI Health Dubai UAE
Author
Ignacio J. Ansotegui
Department of Allergy and Immunology Hospital Quironsalud Bizkaia Bilbao Spain
Author
Antonino Romano
Oasi Research Institute‐IRCCS Troina Italy
Author
Werner Aberer
Department of Dermatology Medical University of Graz Graz Austria
Author
Maria Cristina Artesani
Allergy, Bambino Gesù Children's Hospital Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Rome Italy
Author
Elena Azzolini
Asthma & Allergy Unit IRCCS Humanitas Research Hospital, Rozzano Milan Italy
Author
Bruno Barreto
Department of Allergy and Immunology Para State University Center—CESUPA Belém Brazil
Author
Joan Bartra
Allergy Department Hospital Clinic and IDIBAPS. Universitat de Barcelona Barcelona Spain
Author
Sven Becker
Department for Otorhinolaryngology, Head and Neck Surgery University of Tübingen Tübingen Germany
Author
Bianca Beghe
Respiratory Medicine University of Modena & Reggio Emilia, Azienda Ospedaliera‐Universitaria di Modena Modena Italy
Author
Attilio Boner
Pediatric Unit, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics University of Verona Verona Italy
Author
Ewa Borowiack
Evidence Prime Kraków Poland
Author
Jacques Bouchard
Laval University Quebec City Quebec Canada
Author
Melisande Bourgoin‐Heck
Department of Pediatric Allergology Armand Trousseau University Hospital, Sorbonne University, AP‐HP Paris France
Author
Luisa Brussino
Department of Medical Sciences University of Turin Turin Italy
Author
Roland Buhl
Department of Pulmonary Medicine Mainz University Hospital Mainz Germany
Author
José Antonio Castillo‐Vizuete
Pneumology Department Hospital Universitari Dexeus Barcelona Spain
Author
Denis Charpin
Clinique Des Bronches, Allergie et Sommeil Hôpital Nord Marseille France
Author
Niels H. Chavannes
Department of Public Health and Primary Care Leiden University Medical Centre Leiden the Netherlands
Author
Marta Chełmińska
Department of Pulmonology and Allergology Medical University of Gdańsk Gdańsk Poland
Author
Lei Cheng
Department of Allergology and Otorhinolaryngology The First Affiliated Hospital, Nanjing Medical University Nanjing China
Author
Ekaterine Chkhartishvili
Allergist David Tvildiani Medical University Tbilisi Georgia
Author
Seong H. Cho
University of South Florida College of Médicine, Division of Allergy‐Immunology, Department of Internal Medicine Tampa Florida USA
Author
Herberto Jose Chong‐Neto
Associate Professor of Pediatrics, Division of Allergy and Immunology Federal University of Parana Curitiba Brazil
Author
Deepa Choudhury
Paediatric Allergy Clinic, Department of Dermatology, Amersham Hospital NHS Hospital Trust Amersham UK
Author
Derek K. Chu
Department of Health Research Methods, Evidence, and Impact & Department of Medicine McMaster University Hamilton Ontario Canada
Author
Cemal Cingi
Eskisehir Osmangazi University Medical Faculty, ENT Department Eskisehir Turkey
Author
Enrico Compalati
Scientific & Medical Department Lofarma S.p.A Milan Italy
Author
Raquel Albuquerque Costa
MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal
Author
Olga Mariana Cunha
LAQV@REQUIMTE, Laboratory of Pharmacology, Department of Drug Sciences, Faculty of Pharmacy University of Porto Porto Portugal
Author
Biljana Cvetkovski
Woolcock Institute of Medical Research Sydney Australia
Author
Victoria Cardona‐Dahl
Allergy Section, Department of Internal Medicine Hospital Vall D'hebron Barcelona Spain
Author
Gennaro D'Amato
Division of Respiratory and Allergic Diseases, High Specialty Hospital ‘A Cardarelli’, and Respiratory Allergy School of Specialization in Respiratory Diseases Federico II University of Naples Naples Italy
Author
Janet Davies
Centre for Immunology and Infection Control, School of Biomedical Sciences, Faculty of Health Queensland University of Technology Brisbane Australia
Author
Danilo Di Bona
University of Foggia Department of Medical and Surgical Science Foggia Italy
Author
Sandra N. Gonzalez Diaz
Allergy and Clinical Immunology Centro Regional Hospital Universitario, Universidad Autónoma de Nuevo Leon Monterrey Mexico
Author
Maria V. Dimou
Allergy Department 2nd Pediatric Clinic, University of Athens Athens Greece
Author
Maria Doulaptsi
Department of Otorhinolaryngology, Head and Neck Surgery University of Crete, School of Medicine Heraklion Crete Greece
Author
Renato Ferreira‐da‐Silva
MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal
Author
Radoslaw Gawlik
Department of Internal Diseases, Allergology and Clinical Immunology Medical University of Silesia in Katowice Katowice Poland
Author
Mario Calvo‐Gil
Pediatrics Department Universidad Austral de Chile Valvidia Chile
Author
Ozlem Goksel
Department of Pulmonary Medicine, Division of Immunology, Allergy and Asthma, Laboratory of Occupational and Environmental Respiratory Diseases, Faculty of Medicine Ege University, EgeSAM (Ege University Translational Pulmonary Research Center) Bornova Izmir Türkiye
Author
Maximiliano R. Gómez
Faculty of Health Sciences Catholic University of Salta Salta Argentina
Author
Maia Gotua
Center of Allergy and Immunology, and Georgian Academy of Allergy Asthma, and Clinical Immunology Tbilisi Georgia
Author
Christos Grigoreas
Former President of the Hellenic Society of Allergology and Clinical Immunology, Department of Allergy and Clinical Immunology Air Force General Hospital Athens Greece
Author
Ineta Grisle
Riga East University Hospital Riga Latvia
Author
Maria Antonieta Guzman
Immunology and Allergy Division, Clinical Hospital University of Chile Santiago Chile
Author
Rachel House Tan
Quality Use of Research Medicines Group Woolcock Institute of Medical Research Macquarie Park New South Wales Australia
Author
Michael Hyland
Faculty of Health University of Plymouth Plymouth UK
Author
Despo Ierodiakonou
Department of Primary Care and Population Health University of Nicosia Medical School Nicosia Cyprus
Author
Aspasia Karavelia
Otolaryngology Department General Hospital of Kalamata Kalamata City Greece
Author
Paul Keith
Division of Clinical Immunology and Allergy, Department of Medicine McMaster University Hamilton Ontario Canada
Author
Marta Kisiel
Occupational and Environmental Medicine, Department of Medical Sciences Uppsala University Uppsala Sweden
Author
Tanja Soklic Kosak
ORL SOKLIC KOSAK Ljubljana Slovenia
Author
Mitja Kosnik
University Clinic of Respiratory and Allergic Diseases Golnik Slovenia
Author
Ilgim Vardaloglu Koyuncu
Bagcilar Research and Training Hospital Department of Chest Diseases Istanbul Turkey
Author
Vicky Kritikos
Clinical Management Group, Woolcock Institute of Medical Research Macquarie University Sydney New South Wales Australia
Author
Justyna Litynska
Evidence Prime Kraków Poland
Author
Carlo Lombardi
Departmental Unit of Allergology Clinical Immunology & Pneumology, Istituto Ospedaliero Fondazione Poliambulanza Brescia Italy
Author
Gilles Louis
Department of Public Health University of Liège Liège Belgium
Author
Matteo Martini
Allergy Unit, Department of Internal Medicine University Hospital AOU Delle Marche Ancona Italy
Author
Cem Meço
Department of Otorhinolaryngology, Head and Neck Surgery Ankara University Medical School Ankara Turkey
Author
Eris Mesonjesi
Allergy & Clinical Immunology Department University Hospital Center “Mother Teresa” Tirana Albania
Author
Florin Mihaltan
UMF‐University of Medicine and Pharmacy ‘Carol Davila’, Pneumology Department National Institute of Pneumology ‘Marius Nasta’ Bucharest Romania
Author
Marcin Moniuszko
Department of Allergology and Internal Medicine Medical University of Bialystok Bialystok Poland
Author
Robert N. Naclerio
Department of Otolaryngology‐Head and Neck Surgery Johns Hopkins University Baltimore Maryland USA
Author
Kari C. Nadeau
Department of Environmental Health, Harvard TH Chan School of Public Health and Department of Medicine, Division of Allergy and Inflammation Beth Israel Deaconess Hospital Boston Massachusetts USA
Author
Sophia Neisinger
Institute of Allergology Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt‐Universität Zu Berlin Berlin Germany
Author
Markus Ollert
Department of Infection and Immunity Luxembourg Institute of Health Esch‐sur‐Alzette Luxembourg
Author
Michal Ordak
Department of Pharmacotherapy and Pharmaceutical Care, Faculty of Pharmacy Medical University of Warsaw Warsaw Poland
Author
Giovanni Paoletti
Department of Biomedical Science Humanitas University, Pieve Emanuele Milan Italy
Author
Hae‐Sim Park
Department of Allergy and Clinical Immunology Ajou University School of Medicine Suwon Republic of Korea
Author
Elena Parmelli
Asthma & Allergy Unit IRCCS Humanitas Research Hospital, Rozzano Milan Italy
Author
Edgar Arturo Perdomo‐Flores
Otorhinolaryngology and Neck Surgery Unit San Juan de Dios National Hospital San Miguel El Salvador
Author
José Miguel Fuentes Pérez
Allergist Private Practice Mexico City Mexico
Author
Nhan Pham‐Thi
Ecole Polytechnique de Palaiseau Palaiseau France
Author
Emmanuel Prokopakis
Department of Otorhinolaryngology, Head and Neck Surgery University of Crete, School of Medicine Heraklion Crete Greece
Author
Inês Ribeiro‐Vaz
MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal
Author
Giovanni Rolla
Department of Medical Sciences University of Turin Turin Italy
Author
Jan Romantowski
Department of Allergology Medical University of Gdansk Gdansk Poland
Author
Philippe Rombaux
Department of Otorhinolaryngology Cliniques Universitaires Saint‐Luc Brussels Belgium
Author
Philip W. Rouadi
Department of Otolaryngology‐Head and Neck Surgery Eye and Ear University Hospital Beirut Lebanon
Author
Maia Rukhadze
Center Allergy & Immunology/Geomedi Teaching University Faculty of Medicine Tbilisi Georgia
Author
Dermot Ryan
Usher Institute University of Edinburgh Edinburgh UK
Author
Ewelina Sadowska
Evidence Prime Kraków Poland
Author
Daiju Sakurai
Department of Otorhinolaryngology Yamanashi University Yamanashi Japan
Author
Laila Salameh
Mohammed Bin Rashid University (MBRU) Dubai Health Dubai UAE
Author
Faradiba Serpa Sarquis
Asthma Reference Center—School of Medicine of Santa Casa de Misericórdia of Vitória Espírito Santo Brazil
Author
Elie Serrano
Department of Otorhinolaryngology and Head & Neck Surgery CHU Rangueil‐Larrey Toulouse France
Author
Jane Da Silva
Allergy Service University Hospital Professor Polydoro Ernani de São Thiago (HU‐UFSC/EBSERH) Florianopolis Brazil
Author
Michael Soyka
Otolaryngology‐HNS, University of Zurich University Hospital of Zurich Zurich Switzerland
Author
Krzysztof Specjalski
Department of Allergology Medical University of Gdansk Gdansk Poland
Author
Vesna Tomic‐Spiric
Clinic of Allergology and Immunology University Clinical Center of Serbia Belgrade Serbia
Author
Katarina Stevanovic
Institute of Allergology Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt‐Universität Zu Berlin Berlin Germany
Author
Abirami Subramaniam
Department of Respiratory Medicine, Medical Professorial Unit Tallaght University Hospital & Trinity College Dublin Ireland
Author
Maria Do Ceu Teixeira
Dr Agostinho Neto University Hospital Praia Cabo Verde
Author
Tuuli Thomander
MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal
Author
Martina Vachova
Department of Immunology and Allergology University Hospital and Faculty of Medicine in Pilsen Pilsen Czech Republic
Author
Marianne van Hage
Department of Medicine Solna, Division of Immunology and Respiratory Medicine Karolinska Institutet Stockholm Sweden
Author
Pakit Vichyanond
Samitivej Allergy Institute Bangkok Thailand
Author
Martin Wagenmann
Department of Otorhinolaryngology Heinrich Heine University Düsseldorf, Medical Faculty and University Hospital Düsseldorf Düsseldorf Germany
Author
Fanny Wai San Ko
The Chinese University of Hong Kong Department of Medicine and Therapeutics Hong Kong China
Author
Pascal Werminghaus
ENT and Allergology Düsseldorf Germany
Author
Paraskevi Vicky Xepapadaki
Allergy Department 2nd Pediatric Clinic, University of Athens Athens Greece
Author
Yi‐Kui Xiang
Institute of Allergology Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt‐Universität Zu Berlin Berlin Germany
Author
Qintai Yang
The Third Affiliated Hospital of sun Yat‐Sen University Guangzhou China
Author
Daniela Rivero Yeverino
Servicio de Alergia e Inmunología clínica Hospital Universitario de Puebla Puebla México
Author
Jaron Zuberbier
Department of Otorhinolaryngology Charité—Universitätsmedizin Berlin Berlin Germany
Author
João A. Fonseca
MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal
Abstract (eng)
Background Allergic rhinitis (AR) impacts quality of life, work and school productivity. Over the last years, an important body of evidence resulting from mHealth data has led to a better understanding of AR. Such advances have motivated an EAACI-endorsed update of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines (ARIA 2024–2025). This manuscript presents the ARIA 2024–2025 recommendations for intranasal treatments, one of the mainstays for AR management. Methods The ARIA 2024–2025 guideline panel issued recommendations following the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) evidence-to-decision framework. Several sources of evidence were used to inform panel judgments and recommendations, including systematic reviews, evaluation of mHealth and pharmacovigilance data, as well as a survey of experts on costs. Results Eleven guideline questions concerning intranasal treatments for AR were prioritized, leading to recommendations. Overall, these questions concern the choice between different classes of intranasal medications—most notably, intranasal corticosteroids (INCS), antihistamines (INAH), fixed combinations of INAH+INCS and decongestants—or between different individual medications within each class. Four questions had not been evaluated in previous ARIA guidelines, while for the other three there was a change in the strength or directionality of recommendations. Overall, recommendations point to the suggested use of INAH+INCS over INAH or INCS and INCS over INAH. Conclusion This ARIA 2024–2025 article supports patients, their caregivers, and healthcare professionals in choosing an intranasal treatment. However, decisions on AR treatment should consider the clinical variability of the disease, patients' values, and the affordability of medications.
Remark (eng)
Online Version of Record before inclusion in an issue
Keywords (eng)
Allergic RhinitisGuidelinesIntranasal AntihistaminesIntranasal Corticosteroids
Type (eng)
Language
[eng]
Is in series
Title (eng)
Allergy
ISSN
0105-4538
Issued
2025
Number of pages
23
Publication
Wiley
Date issued
2025
Access rights (eng)
Rights statement (eng)
© 2025 The Author(s)