Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma ( ARIA)‐EAACI 2024–2025 Guidelines: From Evidence‐to‐Decision Frameworks to Digitalised Shared Decision‐Making Algorithms

Title (eng)
Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma ( ARIA)‐EAACI 2024–2025 Guidelines: From Evidence‐to‐Decision Frameworks to Digitalised Shared Decision‐Making Algorithms
Author
Bernardo Sousa‐Pinto
MEDCIDS—Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal
Author
Holger J. Schünemann
Author
Alkis Togias
Author
Boleslaw Samolinski
Author
Arunas Valiulis
Author
Sian Williams
Author
Anna Bedbrook
Author
Wienczyslawa Czarlewski
Author
Mark S. Dykewicz
Author
Cristina Jacomelli
Author
Lucas Leemann
Author
Yuliia Palamarchuk
Author
Ana Margarida Pereira
Author
Maria Teresa Ventura
Author
Juan Jose Yepes‐Nuñez
Author
Giorgio Ciprandi
Author
Bilun Gemicioglu
Author
Brigita Gradauskiene
Author
Piotr Kuna
Author
Violeta Kvedariene
Author
Désirée E. Larenas‐Linnemann
Author
Amir H. A. Latiff
Author
Yousser Mohammad
Author
Ken Ohta
Author
Padukudru A. Mahesh
Author
Author
Frederico S. Regateiro
Author
Nicolas Roche
Author
Mikhail Sofiev
Author
Luís Taborda‐Barata
Author
Charlotte Suppli Ulrik
Author
Marylin Valentin Rostan
Author
Giovanni Viegi
Author
Author
Josep M. Antó
Author
Juan Carlos Ivancevich
Author
Nikolai Khaltaev
Author
Baharudin Abdullah
Author
Mona Al‐Ahmad
Author
Author
Karl‐C Bergmann
Author
Michael S. Blaiss
Author
Fulvio Braido
Author
Paulo Camargos
Author
Pedro Carreiro‐Martins
Author
Thomas Casale
Author
George Christoff
Author
Ieva Cirule
Author
Elisio M. Costa
Author
Philippe Devillier
Author
Dejan Dokic
Author
Elham Hossny
Author
Carla Irani
Author
Zhanat Ispayeva
Author
Kaja Julge
Author
Igor Kaidashev
Author
Kazi S. Bennoor
Author
Helga Kraxner
Author
Author
Marek Kulus
Author
Maciej Kupczyk
Author
Stefania La Grutta
Author
Neven Miculinic
Author
Lan Le Thi Tuyet
Author
Michael Makris
Author
Branislava Milenkovic
Author
Author
Stephen Montefort
Author
André Moreira
Author
Joaquim Mullol
Author
Author
Alla Nakonechna
Author
Hugo E. Neffen
Author
Dieudonné Nyembue
Author
Ismail Ogulur
Author
Yoshitaka Okamoto
Author
Heidi Olze
Author
Author
Constantinos Pitsios
Author
Todor A. Popov
Author
Francesca Puggioni
Author
Santiago Quirce
Author
Agné Ramonaité
Author
Marysia Recto
Author
Menachem Rottem
Author
Marianella Salapatas
Author
Joaquin Sastre
Author
Nicola Scichilone
Author
Juan Carlos Sisul
Author
Dirceu Solé
Author
Manuel E. Soto‐Martinez
Author
Milan Sova
Author
Pongsakorn Tantilipikorn
Author
Ana Todo‐Bom
Author
Ioanna Tsiligianni
Author
Marilyn Urrutia‐Pereira
Author
Erkka Valovirta
Author
Eric Van Ganse
Author
Tuula Vasankari
Author
Dana Wallace
Author
Author
Osman M. Yusuf
Author
Mihaela Zidarn
Author
Sara Gil‐Mata
Author
Manuel Marques‐Cruz
Author
Bassam Mahboub
Author
Ignacio J. Ansotegui
Author
Antonino Romano
Author
Bruno Barreto
Author
Author
Bianca Beghe
Author
Jacques Bouchard
Author
Luisa Brussino
Author
Roland Buhl
Author
Mario Calvo‐Gil
Author
Victoria Cardona Dahl
Author
José Antonio Castillo Vizuete
Author
Denis Charpin
Author
Niels H. Chavannes
Author
Marta Chełmińska
Author
Lei Cheng
Author
Ekaterine Chkhartishvili
Author
Herberto Jose Chong‐Neto
Author
Deepa Choudhury
Author
Derek Chu
Author
Author
Enrico Compalati
Author
Biljana Cvetkovski
Author
Jane Da Silva
Author
Janet Davies
Author
Danilo Di Bona
Author
Maria V. Dimou
Author
Maria Do Ceu Teixeira
Author
Radoslaw Gawlik
Author
Author
Maximiliano R. Gómez
Author
Maia Gotua
Author
Christos Grigoreas
Author
Ineta Grisle
Author
Maria Antonieta Guzman
Author
Rachel House Tan
Author
Michael Hyland
Author
Despo Ierodiakonou
Author
Aspasia Karavelia
Author
Marta Kisiel
Author
Author
Carlo Lombardi
Author
Cem Meço
Author
Eris Mesonjesi
Author
Florin Mihaltan
Author
Marcin Moniuszko
Author
Robert Naclerio
Author
Sophia Neisinger
Author
Author
Edgar Arturo Perdomo‐Flores
Author
Nhan Pham‐Thi
Author
Emmanuel Prokopakis
Author
Daniela Rivero Yeverino
Author
Giovanni Rolla
Author
Jan Romantowski
Author
Maia Rukhadze
Author
Daiju Sakurai
Author
Laila Salameh
Author
Faradiba Serpa Sarquis
Author
Krzysztof Specjalski
Author
Vesna Tomic‐Spiric
Author
Martina Vachova
Author
Ilgim Vardaloglu Koyuncu
Author
Pakit Vichyanond
Author
Fanny Wai San Ko
Author
Pascal Werminghaus
Author
Vicky Paraskevi Xepapadaki
Author
João A. Fonseca
Abstract (eng)
The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines produced their first edition in 1999, with subsequent revisions in 2008, 2010, 2016 and 2019. A new iteration of ARIA—ARIA 2024–2025—in collaboration with EAACI is currently being developed, focusing on the management of allergic rhinitis. ARIA 2024–2025 follows the GRADE framework and is endorsed by the European Academy of Allergy and Clinical Immunology (EAACI). A set of approaches has been used to develop guideline questions, including surveying key opinion leaders and using artificial intelligence (AI)-based tools to analyse web searches on allergic rhinitis and to generate questions. Each prioritised guideline question is assessed through an Evidence-to-Decision (EtD) framework. EtDs support the systematic and transparent formulation of recommendations, comprising 12 criteria for which the best available evidence should be sought. In the context of ARIA-EAACI 2024–2025, such evidence is derived not only from randomised controlled trials but also—among others—from patient-generated data sources that better reflect the affected individuals' perspectives. Moreover, ARIA-EAACI 2024–2025 incorporates evidence on planetary health. Developed guideline recommendations will support the creation of digitalised decision algorithms and care pathways. This paper describes the methodology used to develop the person-centred, digitally enabled and AI-assisted ARIA-EAACI 2024–2025. Among others, it describes (i) the development and prioritisation of guideline questions, (ii) sources of evidence for EtDs and (iii) the development of digitalised decision algorithms and care pathways.
Keywords (eng)
Allergic RhinitisAsthmaENT (rhinitis, sinusitis, nasal polyps…)guidelines
Type (eng)
Language
[eng]
Is in series
Title (eng)
Allergy
Volume
81
Issue
2
ISSN
0105-4538
Issued
2026
Number of pages
27
Publication
Wiley
Date issued
2026
Access rights (eng)
Rights statement (eng)
© 2025 The Author(s)