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Title (en)
Maternal stress effects across generations in a precocial bird
Language
English
Description (en)
Prenatal maternal stress (PMS) is known to shape the phenotype of the first generation offspring (F1) but according to some studies, it could also shape the phenotype of the offspring of the following generations. We previously showed in the Japanese quail that PMS increased the emotional reactivity of F1 offspring in relation to (i) a variation in the levels of some histone post-translational modification (H3K27me3) in their brains and (ii) a modulation of the hormonal composition of the eggs from which they hatched. Here, we wondered whether PMS could also influence the behaviour of the second (F2) and third (F3) generation offspring due to the persistence of the specific marks we identified. Using a principal component analysis, we found that PMS influenced F2 and F3 quail profiles with subtle differences between generations. It increased F2 neophobia, F3 fearfulness and F3 neophobia but only in females. Interestingly, we did not find any variations in the level of histone post-translational modification in F3 brains and we observed inconsistent modulations of androstenedione levels in F1 and F2 eggs. Although they may vary over generations, our results demonstrate that PMS can have phenotypical effects into the third generation.
Keywords (en)
Japanese-Quail Eggs; Prenatal Stress; Yolk-Androgens; Corticosterone Levels; Histone Methylation; Behavior; Growth; Fear; Sex; Albumin
DOI
10.1098/rsos.231826
Author of the digital object
Marion Charrier  (Université de Rennes / Université de Tours / Syndicat des Sélectionneurs Avicoles et Aquacoles Français)
Cécilia Houdelier  (Université de Rennes)
Ludovic Calandreau  (Université de Tours)
Daniel Guémené  ( Syndicat des Sélectionneurs Avicoles et Aquacoles Français / Université de Tours)
Ludovic Dickel  (Université de Rennes)
Anne-Sophie Darmaillacq  (Université de Rennes)
Aline Bertin  (Université de Tours)
Céline Nicolle  (Université de Rennes)
Vincent Coustham  (Université de Tours / Université de Pau et des Pays de l'Adour)
Frédéric Angelier  (Centre d'Etudes Biologiques de Chizé)
Rupert Palme  (University of Veterinary Medicine Vienna)
Marion Georgelin  (Université de Tours)
Maryse Meurisse  (Université de Tours)
Sophie Lumineau  (Université de Rennes)
Isabelle George  (Université de Rennes)
Format
application/pdf
Size
831.5 kB
Licence Selected
CC BY 4.0 International
Type of publication
Article
Name of Publication (en)
Royal Society Open Science
Pages or Volume
17
Volume
11
Number
8
Publisher
The Royal Society
Publication Date
2024