Titel (eng)

Non-additive effects between genotypes: Implications for competitive fitness assays

Autor*in

Changyi Xiao   University of Veterinary Medicine Vienna / Vienna Graduate School of Population Genetics

Christian Schlötterer   University of Veterinary Medicine Vienna

Yiwen Chen   University of Veterinary Medicine Vienna / Vienna Graduate School of Population Genetics

Sara Duarri-Redondo   University of Veterinary Medicine Vienna / Vienna Graduate School of Population Genetics

Dagny A. V. Thorhölludottir   University of Veterinary Medicine Vienna / Vienna Graduate School of Population Genetics

Verlag

Wiley

Beschreibung (eng)

Competitive fitness assays are widely used in evolutionary biology and typically rely on a reference strain to compare different focal genotypes. This approach implicitly relies on the absence of interaction between the competing genotypes. In other words, the performance of the reference strain must not depend on the competitor. This report scrutinized this assumption by competing diverged Drosophila simulans populations against a common reference strain. We detected strong evidence for interaction between the competing genotypes: (1) Frequency-dependent selection was common with opposite effects in genetically diverged populations. (2) Temporal heterogeneity of fitness estimates, which can be partially attributed to a competitor-specific delay in the eclosion of the reference strain. We propose that this inconsistent behavior of the reference strain can be considered a specific case of a genotype × environment interaction. Focal populations could modify the environment of the reference strain, either indirectly by altering the microbiome composition and food availability or directly by genotype-specific cannibalism. Our results provide new insights into the interaction of diverged genotypes and have important implications for the interpretation of competitive fitness assays.

Sprache des Objekts

Englisch

Datum

2023

Rechte

Dieses Werk bzw. dieser Inhalt steht unter einer
CC BY 4.0 - Creative Commons Namensnennung 4.0 International Lizenz.

CC BY 4.0 International

http://creativecommons.org/licenses/by/4.0/

Klassifikation

Drosophila-Melanogaster; Environment Interaction; Dependent Selection; Genetic-Variation; Viability; Populations; Evolution

Mitglied in der/den Collection(s) (1)