Titel (eng)

Immunotherapy of Equine Sarcoids-From Early Approaches to Innovative Vaccines

Autor*in

Christoph Jindra   University of Veterinary Medicine Vienna / Karl Landsteiner University of Health Sciences

Sabine Brandt   University of Veterinary Medicine Vienna

Edmund K. Hainisch   University of Veterinary Medicine Vienna

Verlag

MDPI

Beschreibung (eng)

Horses and other equid species are frequently affected by bovine papillomavirus type 1 and/or 2 (BPV1, BPV2)-induced skin tumors termed sarcoids. Although sarcoids do not metastasize, they constitute a serious health problem due to their BPV1/2-mediated resistance to treatment and propensity to recrudesce in a more severe, multiple form following accidental or iatrogenic trauma. This review provides an overview on BPV1/2 infection and associated immune escape in the equid host and presents early and recent immunotherapeutic approaches in sarcoid management.

Sprache des Objekts

Englisch

Datum

2023

Rechte

Dieses Werk bzw. dieser Inhalt steht unter einer
CC BY 4.0 - Creative Commons Namensnennung 4.0 International Lizenz.

CC BY 4.0 International

http://creativecommons.org/licenses/by/4.0/

Klassifikation

Bovine Papillomavirus Type-1; Virus-Like Particles; Regulatory T-Cell; Leukocyte Antigens; Tumor-Cells; Human Interleukin-2; Immune-Response; Gene-Expression; Dna; Protein

Mitglied in der/den Collection(s) (1)