Titel (eng)

Papillomavirus-like Particles in Equine Medicine

Autor*in

Edmund K Hainisch   University of Veterinary Medicine, Vienna

Sabine Brandt   University of Veterinary Medicine, Vienna

Reinhard Kirnbauer   Medical University of Vienna

Christoph Jindra   University of Veterinary Medicine, Vienna / Karl Landsteiner University of Health Sciences

Verlag

MDPI

Beschreibung (eng)

Papillomaviruses (PVs) are a family of small DNA tumor viruses that can induce benign lesions or cancer in vertebrates. The observation that animal PV capsid-proteins spontaneously self-assemble to empty, highly immunogenic virus-like particles (VLPs) has led to the establishment of vaccines that efficiently protect humans from specific PV infections and associated diseases. We provide an overview of PV-induced tumors in horses and other equids, discuss possible routes of PV transmission in equid species, and present recent developments aiming at introducing the PV VLP-based vaccine technology into equine medicine.

Sprache des Objekts

Englisch

Datum

2023

Rechte

Dieses Werk bzw. dieser Inhalt steht unter einer
CC BY 4.0 - Creative Commons Namensnennung 4.0 International Lizenz.

CC BY 4.0 International

http://creativecommons.org/licenses/by/4.0/

Klassifikation

Humans; Animals; Horses; Papillomaviridaegenetics; Capsid; Capsid Proteinsgenetics

Mitglied in der/den Collection(s) (1)