Title (eng)

Genome-Wide Screening for SNPs Associated with Stature in Diverse Cattle Breeds.

Author

Alexandra S. Abdelmanova   L.K. Ernst Federal Research Center for Animal Husbandry

Natalia A. Zinovieva   L.K. Ernst Federal Research Center for Animal Husbandry

Gottfried Brem   University of Veterinary Medicine Vienna

Margaret S. Fornara   L.K. Ernst Federal Research Center for Animal Husbandry

Nikolay V. Bardukov   L.K. Ernst Federal Research Center for Animal Husbandry

Alexander A. Sermyagin   L.K. Ernst Federal Research Center for Animal Husbandry

Arsen V. Dotsev   L.K. Ernst Federal Research Center for Animal Husbandry

Publishing

MDPI

Description (eng)

Cattle breeds used in industrial production tend to be larger than local cattle, as increased dairy and beef productivity is closely related to stature. This study aimed to identify single nucleotide polymorphisms (SNPs) significantly associated with stature in diverse cattle breeds. Thirteen local and transboundary cattle breeds (n = 670) were divided into two groups according to their stature. The high-stature group included the Angus, Ayrshire, Black-and-White, Holstein, Kholmogor, Yaroslavl, Tagil, and Istoben breeds. The low-stature group included Jersey, Kalmyk, Kyrgyz, Mongolian, and Yakut. The average height at withers was 136.3 +/- 1.6 and 121.6 +/- 2.8 cm in the high- and low-stature groups, respectively. The samples of the 11 breeds were genotyped using high-density DNA arrays. Genotypes of the two remaining breeds were downloaded from the publicly available WIDDE database. Genome-wide association studies revealed seven SNPs strongly associated with stature, including three at 77.3-77.8 cM on BTA4 and four at 24.5-25.2 cM on BTA14. Functional annotation showed the localization within identified regions of genes responsible for growth, exterior characteristics, protein and lipid metabolism, and feed intake. The identified SNPs can be considered useful DNA markers for marker-assisted cattle breeding aimed at increasing stature.

Object languages

English

Date

2022

Rights

Creative Commons License
This work is licensed under a
CC BY 4.0 - Creative Commons Attribution 4.0 International License.

CC BY 4.0 International

http://creativecommons.org/licenses/by/4.0/

Classification

Body-Weight; Plag1; Traits; Growth; Selection; Carcass; Dairy

Member of the Collection(s) (1)

o:605 Publications / University of Veterinary Medicine Vienna