Title
Genome-Wide Screening for SNPs Associated with Stature in Diverse Cattle Breeds.
Language
English
Description (en)
Cattle breeds used in industrial production tend to be larger than local cattle, as increased dairy and beef productivity is closely related to stature. This study aimed to identify single nucleotide polymorphisms (SNPs) significantly associated with stature in diverse cattle breeds. Thirteen local and transboundary cattle breeds (n = 670) were divided into two groups according to their stature. The high-stature group included the Angus, Ayrshire, Black-and-White, Holstein, Kholmogor, Yaroslavl, Tagil, and Istoben breeds. The low-stature group included Jersey, Kalmyk, Kyrgyz, Mongolian, and Yakut. The average height at withers was 136.3 +/- 1.6 and 121.6 +/- 2.8 cm in the high- and low-stature groups, respectively. The samples of the 11 breeds were genotyped using high-density DNA arrays. Genotypes of the two remaining breeds were downloaded from the publicly available WIDDE database. Genome-wide association studies revealed seven SNPs strongly associated with stature, including three at 77.3-77.8 cM on BTA4 and four at 24.5-25.2 cM on BTA14. Functional annotation showed the localization within identified regions of genes responsible for growth, exterior characteristics, protein and lipid metabolism, and feed intake. The identified SNPs can be considered useful DNA markers for marker-assisted cattle breeding aimed at increasing stature.
Keywords (en)
Body-Weight; Plag1; Traits; Growth; Selection; Carcass; Dairy
DOI
10.3390/d14080692
Author of the digital object
Alexandra S.  Abdelmanova  (L.K. Ernst Federal Research Center for Animal Husbandry)
Natalia A.  Zinovieva  (L.K. Ernst Federal Research Center for Animal Husbandry)
Gottfried  Brem  (University of Veterinary Medicine Vienna)
Margaret S.  Fornara  (L.K. Ernst Federal Research Center for Animal Husbandry)
Nikolay V.  Bardukov  (L.K. Ernst Federal Research Center for Animal Husbandry)
Alexander A.  Sermyagin  (L.K. Ernst Federal Research Center for Animal Husbandry)
Arsen V.  Dotsev  (L.K. Ernst Federal Research Center for Animal Husbandry)
Format
application/pdf
Size
418.7 kB
Licence Selected
CC BY 4.0 International
Type of publication
Article
Name of Publication (en)
Diversity
Pages or Volume
9
Volume
14
Number
8
Publisher
MDPI
Publication Date
2022
Content
Details
Object type
PDFDocument
Format
application/pdf
Created
27.03.2024 09:15:09
This object is in collection
Metadata
Veterinärmedizinische Universität Wien (Vetmeduni) | Veterinärplatz 1 | 1210 Wien - Österreich | T +43 1 25077-0 | Web: vetmeduni.ac.at