phaidra.vetmeduni.ac.at o:2780 DOI 10.3390/d14080692 Genome-Wide Screening for SNPs Associated with Stature in Diverse Cattle Breeds. Cattle breeds used in industrial production tend to be larger than local cattle, as increased dairy and beef productivity is closely related to stature. This study aimed to identify single nucleotide polymorphisms (SNPs) significantly associated with stature in diverse cattle breeds. Thirteen local and transboundary cattle breeds (n = 670) were divided into two groups according to their stature. The high-stature group included the Angus, Ayrshire, Black-and-White, Holstein, Kholmogor, Yaroslavl, Tagil, and Istoben breeds. The low-stature group included Jersey, Kalmyk, Kyrgyz, Mongolian, and Yakut. The average height at withers was 136.3 +/- 1.6 and 121.6 +/- 2.8 cm in the high- and low-stature groups, respectively. The samples of the 11 breeds were genotyped using high-density DNA arrays. Genotypes of the two remaining breeds were downloaded from the publicly available WIDDE database. Genome-wide association studies revealed seven SNPs strongly associated with stature, including three at 77.3-77.8 cM on BTA4 and four at 24.5-25.2 cM on BTA14. Functional annotation showed the localization within identified regions of genes responsible for growth, exterior characteristics, protein and lipid metabolism, and feed intake. The identified SNPs can be considered useful DNA markers for marker-assisted cattle breeding aimed at increasing stature. eng Body-Weight; Plag1; Traits; Growth; Selection; Carcass; Dairy 2024-03-27T09:18:41.966Z LOMv1.0 Author BEGIN:VCARD VERSION:3.0 N:Abdelmanova;Alexandra S.; FN:Alexandra S. Abdelmanova END:VCARD BEGIN:VCARD VERSION:3.0 N:Zinovieva;Natalia A.; FN:Natalia A. Zinovieva X-ORCID:https://orcid.org/0000-0003-4017-6863 END:VCARD BEGIN:VCARD VERSION:3.0 N:Brem;Gottfried; FN:Gottfried Brem X-ORCID:https://orcid.org/0000-0002-7522-0708 END:VCARD BEGIN:VCARD VERSION:3.0 N:Fornara;Margaret S.; FN:Margaret S. Fornara X-ORCID:https://orcid.org/0000-0002-8844-177X END:VCARD BEGIN:VCARD VERSION:3.0 N:Bardukov;Nikolay V.; FN:Nikolay V. Bardukov END:VCARD BEGIN:VCARD VERSION:3.0 N:Sermyagin;Alexander A.; FN:Alexander A. Sermyagin X-ORCID:https://orcid.org/0000-0002-1799-6014 END:VCARD BEGIN:VCARD VERSION:3.0 N:Dotsev;Arsen V.; FN:Arsen V. Dotsev X-ORCID:https://orcid.org/0000-0003-3418-2511 END:VCARD https://w3id.org/kim/hcrt/scheme https://w3id.org/kim/hcrt/text Textdokument Text LOMv1.0 yes https://creativecommons.org/licenses/by/4.0 application/pdf 428723 https://phaidra.vetmeduni.ac.at/o:2780 https://phaidra.vetmeduni.ac.at/api/object/o:2780/thumbnail LOMv1.0 discipline