Sensory nerve conduction stimulus threshold measurements of the infraorbital nerve and its applicability as a diagnostic tool in horses with trigeminal-mediated headshaking

Jasmin Nicole Nessler; Julien Delarocque; Tanja Kloock; Lara Twele; Stephan Neudeck; Nina Meyerhoff; Franziska Riese; Jessica-M V Cavalleri; Andrea Tipold; Karsten Feige; Tobias Niebuhr

doi:10.1186/s12917-024-04068-x

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Title (eng)

Sensory nerve conduction stimulus threshold measurements of the infraorbital nerve and its applicability as a diagnostic tool in horses with trigeminal-mediated headshaking

Author

Jasmin Nicole Nessler

Julien Delarocque

Tanja Kloock

Lara Twele

Stephan Neudeck

Nina Meyerhoff

Franziska Riese

Jessica-M V Cavalleri

University of Veterinary Medicine Vienna

Andrea Tipold

Karsten Feige

Tobias Niebuhr

Abstract (eng)

To determine whether sensory nerve conduction stimulus threshold measurements of the infraorbital nerve are able to differentiate horses with idiopathic trigeminal-mediated headshaking (i-TMHS) from healthy horses and from horses with secondary trigeminal-mediated headshaking (s-TMHS). In a prospective trial, headshaking horses were examined using a standardized diagnostic protocol, including advanced diagnostics such as computed tomography and 3-Tesla-magnetic resonance imaging (MRI), to differentiate s-TMHS from i-TMHS. Clinically healthy horses served as controls. Within this process, patients underwent general anesthesia, and the minimal sensory nerve conduction stimulus threshold (SNCT) of the infraorbital nerve was measured using a bipolar concentric needle electrode. Sensory nerve action potentials (SNAP) were assessed in 2.5-5 mA intervals. Minimal SNCT as well as additional measurements were calculated.In 60 horses, SNAP could be recorded, of which 43 horses had i-TMHS, six had suspected s-TMHS, three horses had non-facial headshaking, and eight healthy horses served as controls. Controls had a minimal SNCT ≥ 15 mA, whereas 14/43 horses with i-TMHS and 2/6 horses with s-TMHS showed a minimal SNCT ≤ 10 mA. Minimal SNCT ≤ 10 mA showed 100% specificity to distinguish TMHS from controls, but the sensitivity was only 41%.A minimal SNCT of the infraorbital nerve ≤ 10 mA was able to differentiate healthy horses from horses with TMHS. Nevertheless, a higher minimal SNCT did not exclude i-TMHS or s-TMHS and minimal SNCT does not distinguish s-TMHS from i-TMHS.

Keywords (eng)

Trigeminal-mediated Head ShakingSensory Nerve Conduction Stimulus ThresholdInfraorbital NerveNeuropathy

Type (eng)

journal article

Language

[eng]

Persistent identifier

https://phaidra.vetmeduni.ac.at/o:4288

DOI

10.1186/s12917-024-04068-x

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Title (eng)