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    <ns1:title language="en">Cdk6: At the interface of Rb and p53</ns1:title>
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    <ns1:description language="en">In cancer the activity of cyclin-dependent kinase 4-(CDK4) and cyclin-dependent kinase 6 (CDK6)-cyclin complexes are frequently altered with enhanced CDK6 expression found in hematopoietic malignancies. Our latest findings show a so far unknown role of Cdk6 during oncogene-induced stress and transformation. Therein Cdk6 antagonizes p53 responses and subsequently shapes the critical decision between survival and apoptosis in pre-leukemic cells.</ns1:description>
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    <ns12:name_magazine language="de">Molecular &amp; Cellular Oncology</ns12:name_magazine>
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