
<resource xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:datacite="http://datacite.org/schema/kernel-4" xmlns="http://namespace.openaire.eu/schema/oaire/" xsi:schemaLocation="http://namespace.openaire.eu/schema/oaire/ https://www.openaire.eu/schema/repo-lit/4.0/openaire.xsd">
  
<datacite:identifier identifierType="URL">https://phaidra.vetmeduni.ac.at/o:5577</datacite:identifier>

  
<datacite:titles>
  
<datacite:title xml:lang="en">Inclusion Body Hepatitis (IBH) Outbreaks Following Vertical Transmission of Fowl Adenovirus Serotype 11 (FAdV-11), Species D: A Strain with Regional Persistence and Global Presence</datacite:title>

  
</datacite:titles>

  
<datacite:creators>
  
<datacite:creator>
  
<datacite:creatorName nameType="Personal">Grafl, Beatrice</datacite:creatorName>

  
<datacite:givenName>Beatrice</datacite:givenName>

  
<datacite:familyName>Grafl</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0009-0006-1976-0490</datacite:nameIdentifier>

  
<datacite:affiliation>University of Veterinary Medicine Vienna. Clinical Centre for Population Medicine in Fish, Pig and Poultry</datacite:affiliation>

  
</datacite:creator>

  
<datacite:creator>
  
<datacite:creatorName nameType="Personal">Mitsch, Peter</datacite:creatorName>

  
<datacite:givenName>Peter</datacite:givenName>

  
<datacite:familyName>Mitsch</datacite:familyName>

  
</datacite:creator>

  
<datacite:creator>
  
<datacite:creatorName nameType="Personal">Wiesinger, Ernst</datacite:creatorName>

  
<datacite:givenName>Ernst</datacite:givenName>

  
<datacite:familyName>Wiesinger</datacite:familyName>

  
</datacite:creator>

  
<datacite:creator>
  
<datacite:creatorName nameType="Personal">Ziegerhofer, Josef</datacite:creatorName>

  
<datacite:givenName>Josef</datacite:givenName>

  
<datacite:familyName>Ziegerhofer</datacite:familyName>

  
</datacite:creator>

  
<datacite:creator>
  
<datacite:creatorName nameType="Personal">Bilic, Ivana</datacite:creatorName>

  
<datacite:givenName>Ivana</datacite:givenName>

  
<datacite:familyName>Bilic</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0003-3296-5117</datacite:nameIdentifier>

  
<datacite:affiliation>University of Veterinary Medicine Vienna. Clinical Centre for Population Medicine in Fish, Pig and Poultry</datacite:affiliation>

  
</datacite:creator>

  
<datacite:creator>
  
<datacite:creatorName nameType="Personal">Hess, Claudia</datacite:creatorName>

  
<datacite:givenName>Claudia</datacite:givenName>

  
<datacite:familyName>Hess</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0002-3535-5157</datacite:nameIdentifier>

  
<datacite:affiliation>University of Veterinary Medicine Vienna. Clinical Centre for Population Medicine in Fish, Pig and Poultry</datacite:affiliation>

  
</datacite:creator>

  
<datacite:creator>
  
<datacite:creatorName nameType="Personal">Liebhart, Dieter</datacite:creatorName>

  
<datacite:givenName>Dieter</datacite:givenName>

  
<datacite:familyName>Liebhart</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0003-2412-1248</datacite:nameIdentifier>

  
<datacite:affiliation>University of Veterinary Medicine Vienna. Clinical Centre for Population Medicine in Fish, Pig and Poultry</datacite:affiliation>

  
</datacite:creator>

  
<datacite:creator>
  
<datacite:creatorName nameType="Personal">Hess, Michael</datacite:creatorName>

  
<datacite:givenName>Michael</datacite:givenName>

  
<datacite:familyName>Hess</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0002-6991-0120</datacite:nameIdentifier>

  
<datacite:affiliation>University of Veterinary Medicine Vienna. Clinical Centre for Population Medicine in Fish, Pig and Poultry</datacite:affiliation>

  
</datacite:creator>

  
</datacite:creators>

  
<dc:publisher>MDPI</dc:publisher>

  
<resourceType resourceTypeGeneral="literature" uri="http://purl.org/coar/resource_type/c_6501">journal article</resourceType>

  
<datacite:rights rightsURI="http://purl.org/coar/access_right/c_abf2">open access</datacite:rights>

  
<dc:language>eng</dc:language>

  
<dc:description xml:lang="en">In recent years, outbreaks of inclusion body hepatitis (IBH) have been reported with increasing frequency worldwide. In Austria, the presence of fowl aviadenoviruses (FAdVs) and/or IBH has been documented sporadically. The present report describes a surge of natural IBH cases in fifteen Ross 308 broiler flocks. The clinical picture was characterized by the sudden onset of increased mortality in birds 3 to 15 days of age, persisting for approximately one week, resulting in cumulative flock mortality ranging from 2% to 27%. The main pathological findings were hepatitis with diffuse necrotic foci and petechial hemorrhages with intranuclear inclusion bodies by histology. FAdV was detected in liver samples from all affected flocks. Based upon partial hexon sequence analysis, FAdV serotype-11, species-D (FAdV-11, FAdV-D) was identified, showing complete sequence identity among broiler-derived strains and high identity with previous isolates from Austria and globally IBH-associated isolates. Furthermore, FAdV-11 DNA was detected in dead-in-shell embryos collected during the ongoing outbreak, originating from one suspect broiler breeder flock, confirming vertical transmission. Serological investigations of the suspect breeders confirmed the FAdV-11 infections within the studied timeframe. In conclusion, investigations confirmed vertical transmission of FAdV-11 and subsequent manifestation of IBH in broilers under field conditions, highlighting the epidemiological importance of broiler breeders in IBH outbreaks.</dc:description>

  
<datacite:subjects>
  
<datacite:subject xml:lang="en">inclusion body hepatitis</datacite:subject>

  
<datacite:subject xml:lang="en">fowl adenovirus serotype 11</datacite:subject>

  
<datacite:subject xml:lang="en">broiler</datacite:subject>

  
<datacite:subject xml:lang="en">broiler breeder</datacite:subject>

  
<datacite:subject xml:lang="en">vertical transmission</datacite:subject>

  
<datacite:subject xml:lang="en">mortality</datacite:subject>

  
</datacite:subjects>

  
<licenseCondition uri="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</licenseCondition>

  
<file accessRightsURI="http://purl.org/coar/access_right/c_abf2" mimeType="application/pdf" objectType="fulltext">https://phaidra.vetmeduni.ac.at/api/object/o:5577/download</file>

  
<datacite:alternateIdentifiers>
  
<datacite:alternateIdentifier alternateIdentifierType="DOI">10.3390/poultry5020025</datacite:alternateIdentifier>

  
</datacite:alternateIdentifiers>

  
<datacite:relatedIdentifiers>
  
<datacite:relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://phaidra.vetmeduni.ac.at/o:605</datacite:relatedIdentifier>

  
</datacite:relatedIdentifiers>

  
<dc:format>application/pdf</dc:format>

  
<dc:source xml:lang="en">Poultry</dc:source>

  
<dc:source>issn:2674-1164</dc:source>

  
<version uri="http://purl.org/coar/version/c_970fb48d4fbd8a85">VoR</version>

  
<citationTitle>Poultry</citationTitle>

  
<citationVolume>5</citationVolume>

  
<citationIssue>2</citationIssue>

  
<datacite:sizes>
  
<datacite:size>2.87 MB</datacite:size>

  
</datacite:sizes>

  
<datacite:dates>
  
<datacite:date dateType="Issued">2026</datacite:date>

  
</datacite:dates>

  
</resource>