https://phaidra.vetmeduni.ac.at/o:5382 Regulation of sebaceous gland homeostasis and sebum secretion by the ERBB receptor family Hommel, Theresa Theresa Hommel 0009-0009-0922-9948 University of Veterinary Medicine Vienna Schneider, Marlon R. Marlon R. Schneider 0000-0002-9570-3491 Dahlhoff, Maik Maik Dahlhoff 0000-0001-9189-7631 University of Veterinary Medicine Vienna Elsevier journal article open access eng ERBB receptors are underappreciated regulators of cellular processes in the sebaceous gland (SG). They control sebocyte proliferation, differentiation, and lipid production - mechanisms that are essential for SG homeostasis, sebum secretion, and skin health. Also, impaired ERBB signaling is associated with diseases such as acne, SG hyperplasia, or skin adverse effects to some cancer therapies. By addressing current findings and unsolved aspects of ERBB signaling in the SG, this review aims to encourage deeper investigation to identify potential therapeutic strategies for common and chronic skin conditions. Biomolecules Molecular Mechanism Of Gene Regulation Cell Biology http://creativecommons.org/licenses/by/4.0/ https://phaidra.vetmeduni.ac.at/api/object/o:5382/download 10.1016/j.isci.2026.114834 https://phaidra.vetmeduni.ac.at/o:605 application/pdf iScience issn:2589-0042 VoR iScience 29 3 2.18 MB 2026