https://phaidra.vetmeduni.ac.at/o:5205 Toward a roadmap for addressing today's health dilemma–The 101-statement consensus report Wirnitzer, Katharina C. Katharina C. Wirnitzer Motevalli, Mohamad Mohamad Motevalli Tanous, Derrick R. Derrick R. Tanous Drenowatz, Clemens Clemens Drenowatz Moser, Maximilian Maximilian Moser Cramer, Holger Holger Cramer Rosemann, Thomas Thomas Rosemann Wagner, Karl-Heinz Karl-Heinz Wagner Michalsen, Andreas Andreas Michalsen Knechtle, Beat Beat Knechtle Fras, Zlatko Zlatko Fras Ritskes-Hoitinga, Merel Merel Ritskes-Hoitinga Marques, Adilson Adilson Marques Mis, Nataša Fidler Nataša Fidler Mis Stanford, Fatima C. Fatima C. Stanford Schubert, Christian Christian Schubert Goswami, Nandu Nandu Goswami Leitzmann, Claus Claus Leitzmann Fredriksen, Per Morten Per Morten Fredriksen Ruedl, Gerhard Gerhard Ruedl Wilflingseder, Doris Doris Wilflingseder 0000-0002-5888-5118 University of Veterinary Medicine Vienna Lima, Rodrigo A. Rodrigo A. Lima Kessler, Christian Christian Kessler Jeitler, Michael Michael Jeitler Khan, Naim A. Naim A. Khan Joulaei, Hassan Hassan Joulaei Fatemi, Maryam Maryam Fatemi Knight, Andrew Andrew Knight Kratky, Karl W. Karl W. Kratky Palmer, Kara K. Kara K. Palmer Haditsch, Bernd Bernd Haditsch Jakse, Bostjan Bostjan Jakse Kofler, Walter Walter Kofler Pfeiffer, Tomas Tomas Pfeiffer Cordova-Pozo, Kathya Kathya Cordova-Pozo Tortella, Patrizia Patrizia Tortella Straub, Simon Simon Straub Lynch, Heidi Heidi Lynch Schätzer, Manuel Manuel Schätzer Krishnan, Anupama Anupama Krishnan Fathima A., Shahnaz Shahnaz Fathima A. Gatterer, Lukas Lukas Gatterer Kriwan, Fabian Fabian Kriwan Abhishek, Mittal Mittal Abhishek Nandgaonkar, Hemant Hemant Nandgaonkar Nandgaonkar, Shalaka Shalaka Nandgaonkar Adedara, Abiola O. Abiola O. Adedara Haro, Josep M. Josep M. Haro Gericke, Corina Corina Gericke Neumann, Gaby Gaby Neumann Akhtar, Aysha Aysha Akhtar Rashidlamir, Amir Amir Rashidlamir Thangavelu, Madan Madan Thangavelu Ngoumou, Gonza B. Gonza B. Ngoumou Perpék, Éva Éva Perpék Klaper, Michael Michael Klaper Bhattacharya, Bhaswati Bhaswati Bhattacharya Kirschner, Werner Werner Kirschner Bessems, Kathelijne M. H. H. Kathelijne M. H. H. Bessems Jones, Peter Peter Jones Peoples, Gregory Gregory Peoples Bescos, Raul Raul Bescos Duftner, Christina Christina Duftner Seifert, Georg Georg Seifert Frontiers Media SA journal article open access eng Importance: In recent decades there has been an expansion in the quantity and quality of scientific findings and guidelines on different health topics to promote individual and public health status. Reports also indicate that there has been a simultaneous increase in the financial burden of disease, including trillions spent on healthcare resources by governments worldwide (predominantly in developing countries) to address health concerns. At the same time, personal health behavior is well-known as efficient and cost-free, holding four times the potential to prevent early death compared to health care. Despite this knowledge, data show that the increasing prevalence of unhealthy lifestyles and the associated chronic diseases, especially in Western societies, still need to be controlled. This circumstance exemplifies today‘s global health dilemma, which alarms the inadequacy of ongoing efforts to address the existing health concerns worldwide. Setting, insights, and observations: Three international, multidisciplinary, and inter-university events (two scientific conferences and one tertiary education symposium) were held in Austria (Innsbruck) between 2020 and 2022 to discourse, discuss, and debate these concerns. Two hundred eighty-four experts from 76 universities, organizations, and stakeholders spanning 31 nations and five continents participated in this international research and knowledge exchange to address today's global health dilemma. The latest scientific findings were discussed to develop practical strategies for improving lifestyle behavior and focus on the dual “Healthy Eating & Active Living” approach as a minimum recommendation for sustainable lifelong health and care. The expert panel debated crucial research priorities and future policies, identified gaps and untapped potential in basic health approaches that have been grossly neglected, and approved the evidence-based 101 consensus statements presented. Conclusions and relevance: These endeavors aim to develop novel and effective interventions that address the needs of individuals and communities and promote optimal health status. Prevention Public Health Chronic Diseases Vegan Plant-based Physical Activity Behavior Animal Experiment http://creativecommons.org/licenses/by/4.0/ https://phaidra.vetmeduni.ac.at/api/object/o:5205/download 10.3389/fnut.2025.1676080 https://phaidra.vetmeduni.ac.at/o:605 application/pdf Frontiers in Nutrition issn:2296-861X VoR Frontiers in Nutrition 12 4.30 MB 2025