phaidra.vetmeduni.ac.at o:3891 DOI 10.3390/v17010059 Feline Papillomatosis Different types of feline papillomaviruses (PVs) are associated with a variety of skin lesions and neoplasia, such as papillomas and cell carcinomas, but the virus can also be found in healthy skin. In this review, the European Advisory Board on Cat Diseases (ABCD), a scientifically independent board of veterinary experts on feline infectious diseases from 11 European Countries, discusses the current knowledge of feline PV infections. Cats most likely become infected through lesions or abrasions of the skin. Most PV infections remain asymptomatic. Besides cat-specific PVs, DNA sequences most closely related to human and bovine PVs have been detected in feline skin lesions. Diagnosis is supported by the histological detection of PV-induced cell changes and intralesional detection of viral antigen (immunostaining) or viral DNA (in situ hybridization). Immunostaining of p16CDKN2A protein (p16) can be performed as a proxy marker for PV-induced neoplasms. There is no specific treatment for PV-induced skin lesions. Spontaneous regression commonly occurs. In the case of invasive squamous cell carcinoma (ISCC), complete excision should be considered, if possible. eng Cats Cat Diseases Virology Cat Diseases Diagnosis Animals Papilloma Virology Papilloma Veterinary Papilloma Pathology Papillomavirus Infections Virology Papillomavirus Infections Veterinary Papillomavirus Infections Diagnosis Papillomaviridae Genetics Papillomaviridae Isolation & purification Skin Neoplasms Veterinary Skin Neoplasms Virology Skin Neoplasms Pathology DNA, Viral Genetics Skin Pathology Skin Virology 2025-03-04T09:13:02.829Z LOMv1.0 Author BEGIN:VCARD VERSION:3.0 N:Egberink;Herman; FN:Herman Egberink X-ORCID:https://orcid.org/0000-0001-6852-5936 END:VCARD BEGIN:VCARD VERSION:3.0 N:Hartmann;Katrin; FN:Katrin Hartmann X-ORCID:https://orcid.org/0000-0002-5256-863X END:VCARD BEGIN:VCARD VERSION:3.0 N:Mueller;Ralf; FN:Ralf Mueller END:VCARD BEGIN:VCARD VERSION:3.0 N:Pennisi;Maria Grazia; FN:Maria Grazia Pennisi X-ORCID:https://orcid.org/0000-0002-3169-4194 END:VCARD BEGIN:VCARD VERSION:3.0 N:Belák;Sándor; FN:Sándor Belák X-ORCID:https://orcid.org/0000-0002-2486-268X END:VCARD BEGIN:VCARD VERSION:3.0 N:Tasker;Séverine; FN:Séverine Tasker X-ORCID:https://orcid.org/0000-0002-4059-1402 END:VCARD BEGIN:VCARD VERSION:3.0 N:Möstl;Karin; FN:Karin Möstl END:VCARD BEGIN:VCARD VERSION:3.0 N:Addie;Diane D.; FN:Diane D. Addie X-ORCID:https://orcid.org/0000-0001-7843-2661 END:VCARD BEGIN:VCARD VERSION:3.0 N:Boucraut-Baralon;Corine; FN:Corine Boucraut-Baralon END:VCARD BEGIN:VCARD VERSION:3.0 N:Frymus;Tadeusz; FN:Tadeusz Frymus X-ORCID:https://orcid.org/0000-0002-9160-1455 END:VCARD BEGIN:VCARD VERSION:3.0 N:Hofmann-Lehmann;Regina; FN:Regina Hofmann-Lehmann X-ORCID:https://orcid.org/0000-0001-9750-4296 END:VCARD BEGIN:VCARD VERSION:3.0 N:Marsilio;Fulvio; FN:Fulvio Marsilio X-ORCID:https://orcid.org/0000-0001-9552-1199 END:VCARD BEGIN:VCARD VERSION:3.0 N:Thiry;Etienne; FN:Etienne Thiry X-ORCID:https://orcid.org/0000-0002-9585-7933 END:VCARD BEGIN:VCARD VERSION:3.0 N:Truyen;Uwe; FN:Uwe Truyen END:VCARD BEGIN:VCARD VERSION:3.0 N:Hosie;Margaret J.; FN:Margaret J. Hosie X-ORCID:https://orcid.org/0000-0002-4313-5023 END:VCARD https://w3id.org/kim/hcrt/scheme https://w3id.org/kim/hcrt/text Textdokument Text LOMv1.0 yes https://creativecommons.org/licenses/by/4.0 application/pdf 972790 https://phaidra.vetmeduni.ac.at/o:3891 https://phaidra.vetmeduni.ac.at/api/object/o:3891/thumbnail LOMv1.0 discipline