{"@context":{"aiiso":"http:\/\/purl.org\/vocab\/aiiso\/schema#","arm":"https:\/\/ld4p.github.io\/arm\/core\/ontology\/0.1\/","bf":"http:\/\/id.loc.gov\/ontologies\/bibframe\/","bib":"https:\/\/bibliotek-o.org\/","bibo":"http:\/\/purl.org\/ontology\/bibo\/","cito":"http:\/\/purl.org\/spar\/cito\/","classSchemes":"http:\/\/id.loc.gov\/vocabulary\/classSchemes","dbo":"http:\/\/dbpedia.org\/ontology\/","dce":"http:\/\/purl.org\/dc\/elements\/1.1\/","dcmitype":"http:\/\/dublincore.org\/documents\/2000\/07\/11\/dcmi-type-vocabulary\/#","dcterms":"http:\/\/purl.org\/dc\/terms\/","ebucore":"http:\/\/www.ebu.ch\/metadata\/ontologies\/ebucore\/ebucore","edm":"http:\/\/www.europeana.eu\/schemas\/edm\/","foaf":"http:\/\/xmlns.com\/foaf\/spec\/#","frap":"http:\/\/purl.org\/cerif\/frapo","identifiers":"http:\/\/id.loc.gov\/vocabulary\/identifiers","ids":"http:\/\/id.loc.gov\/vocabulary\/identifiers\/","opaque":"http:\/\/opaquenamespace.org\/","pcdm":"http:\/\/pcdm.org\/models#","phaidra":"https:\/\/phaidra.org\/ontology\/","rdam":"http:\/\/rdaregistry.info\/Elements\/m\/","rdau":"http:\/\/rdaregistry.info\/Elements\/u\/","rdax":"http:\/\/rdaregistry.info\/Elements\/x\/","rdf":"http:\/\/www.w3.org\/1999\/02\/22-rdf-syntax-ns#","rdfs":"https:\/\/www.w3.org\/TR\/rdf-schema\/","relators":"http:\/\/id.loc.gov\/vocabulary\/relators","role":{"@context":{"aut":{"@container":"@list","@id":"http:\/\/id.loc.gov\/vocabulary\/relators\/aut"}}},"schema":"http:\/\/schema.org\/","skos":"http:\/\/www.w3.org\/2004\/02\/skos\/core#","skosxl":"http:\/\/www.w3.org\/2008\/05\/skos-xl"},"@id":"https:\/\/phaidra.vetmeduni.ac.at\/o:3859","bf:note":[{"@type":"bf:Summary","skos:prefLabel":[{"@language":"eng","@value":"Optical coherence tomography (OCT) images are prone to image artifacts due to the birefringence of the sample or the optical system when a polarized light source is used for imaging. These artifacts can lead to degraded image quality and diagnostic information.We aim to mitigate these birefringence-related artifacts in OCT images by adding a depolarizer module in the reference arm of the interferometer.We investigated different configurations of liquid crystal patterned retarders as pseudo-depolarizers in the reference arm of OCT setups. We identified the most effective depolarization module layout for polarization artifact suppression for a spectral-domain OCT system based on a Michelson and a Mach-Zehnder interferometer.The performance of our approach was demonstrated in an achromatic quarter-wave plate allowing the selection of a variety of sample polarization states. A substantial improvement of the OCT signal magnitude was observed after placing the optimal depolarizer configuration, reducing the cross-polarization artifact from 5.7 to 1.8 dB and from 8.0 to 1.0 dB below the co-polarized signal for the fiber-based Michelson and Mach-Zehnder setup, respectively. An imaging experiment in the birefringent scleral tissue of a post-mortem alpine marmot eye and a mouse tail specimen further showcased a significant improvement in the detected signal intensity and an enhanced OCT image quality followed by a drastic elimination of the birefringence-related artifacts.Our study presents a simple yet cost-effective technique to mitigate birefringence-related artifacts in OCT imaging. This method can be readily implemented in existing OCT technology and improve the effectiveness of various OCT imaging applications in biomedicine."}]}],"bf:provisionActivity":[{"@type":"bf:Publication","bf:agent":[{"@type":"schema:Organization","schema:name":[{"@value":"Spie"}]}]}],"dce:rights":[{"@language":"eng","@value":"© 2024 The Authors"}],"dce:subject":[{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Tomography, Optical Coherence Methods"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Tomography, Optical Coherence Instrumentation"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Birefringence"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Artifacts"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Animals"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Mice"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Equipment Design"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Interferometry Methods"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Interferometry Instrumentation"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Image Processing, Computer-Assisted Methods"}]}],"dce:title":[{"@type":"bf:Title","bf:mainTitle":[{"@language":"eng","@value":"Polarization-insensitive optical coherence tomography using pseudo-depolarized reference light for mitigating birefringence-related image artifacts"}]}],"dcterms:accessRights":[{"@type":"skos:Concept","skos:exactMatch":["https:\/\/pid.phaidra.org\/vocabulary\/QW5R-NG4J"],"skos:prefLabel":[{"@language":"eng","@value":"open access"}]}],"dcterms:issued":["2024"],"dcterms:language":["eng"],"dcterms:type":[{"@type":"skos:Concept","skos:exactMatch":["https:\/\/pid.phaidra.org\/vocabulary\/69ZZ-2KGX"],"skos:prefLabel":[{"@language":"eng","@value":"Text"},{"@language":"deu","@value":"Text"}]}],"ebucore:filename":["J_107222.pdf"],"ebucore:hasMimeType":["application\/pdf"],"edm:hasType":[{"@type":"skos:Concept","skos:exactMatch":["https:\/\/pid.phaidra.org\/vocabulary\/VKA6-9XTY"],"skos:prefLabel":[{"@language":"eng","@value":"journal article"},{"@language":"deu","@value":"Wissenschaftlicher Artikel"}]}],"edm:rights":["http:\/\/creativecommons.org\/licenses\/by\/4.0\/"],"oaire:version":[{"@type":"skos:Concept","skos:exactMatch":["https:\/\/pid.phaidra.org\/vocabulary\/PMR8-3C8D"],"skos:prefLabel":[{"@language":"eng","@value":"version of record (published version)"}]}],"rdam:P30004":[{"@type":"ids:doi","@value":"10.1117\/1.JBO.29.11.116001"}],"rdau:P60193":[{"@type":"schema:CreativeWork","bibo:issue":["11"],"bibo:volume":["29"],"dce:title":[{"@type":"bf:Title","bf:mainTitle":[{"@language":"eng","@value":"Journal of Biomedical Optics"}]}],"dcterms:issued":["2024"],"ids:issn":["1560-2281"]}],"role:aut":[{"@type":"schema:Person","schema:familyName":[{"@value":"Varaka"}],"schema:givenName":[{"@value":"Maria"}],"skos:exactMatch":[{"@type":"ids:orcid","@value":"0000-0003-1113-5907"}]},{"@type":"schema:Person","schema:familyName":[{"@value":"Merkle"}],"schema:givenName":[{"@value":"Conrad W."}]},{"@type":"schema:Person","schema:familyName":[{"@value":"May"}],"schema:givenName":[{"@value":"Lucas"}]},{"@type":"schema:Person","schema:familyName":[{"@value":"Fanjul-Vélez"}],"schema:givenName":[{"@value":"Félix"}]},{"@type":"schema:Person","schema:familyName":[{"@value":"Worm"}],"schema:givenName":[{"@value":"Sybren"}],"skos:exactMatch":[{"@type":"ids:orcid","@value":"0009-0008-3243-4491"}]},{"@type":"schema:Person","schema:familyName":[{"@value":"Augustin"}],"schema:givenName":[{"@value":"Marco"}]},{"@type":"schema:Person","schema:familyName":[{"@value":"Lee"}],"schema:givenName":[{"@value":"Hsiang-Chieh"}],"skos:exactMatch":[{"@type":"ids:orcid","@value":"0000-0002-2976-6195"}]},{"@type":"schema:Person","schema:familyName":[{"@value":"Wöhrer"}],"schema:givenName":[{"@value":"Adelheid"}],"skos:exactMatch":[{"@type":"ids:orcid","@value":"0000-0001-8435-8189"}]},{"@type":"schema:Person","schema:affiliation":[{"@type":"schema:Organization","schema:name":[{"@value":"University of Veterinary Medicine Vienna"}],"skos:exactMatch":["https:\/\/ror.org\/01w6qp003"]}],"schema:familyName":[{"@value":"Glösmann"}],"schema:givenName":[{"@value":"Martin"}],"skos:exactMatch":[{"@type":"ids:orcid","@value":"0000-0002-2094-3247"}]},{"@type":"schema:Person","schema:familyName":[{"@value":"Baumann"}],"schema:givenName":[{"@value":"Bernhard"}],"skos:exactMatch":[{"@type":"ids:orcid","@value":"0000-0001-6419-1932"}]}],"schema:numberOfPages":["17"]}