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<datacite:identifier identifierType="URL">https://phaidra.vetmeduni.ac.at/o:3531</datacite:identifier>

  
<datacite:titles>
  
<datacite:title xml:lang="en">Empirical and model-based evidence for a negligible role of cattle in peste des petits ruminants virus transmission and eradication</datacite:title>

  
</datacite:titles>

  
<datacite:creators>
  
<datacite:creator>
  
<datacite:creatorName nameType="Personal">Herzog, Catherine M.</datacite:creatorName>

  
<datacite:givenName>Catherine M.</datacite:givenName>

  
<datacite:familyName>Herzog</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0003-3021-888X</datacite:nameIdentifier>

  
<datacite:affiliation>Pennsylvania State University</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Kapur, Vivek</datacite:creatorName>

  
<datacite:givenName>Vivek</datacite:givenName>

  
<datacite:familyName>Kapur</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0002-9648-0138</datacite:nameIdentifier>

  
<datacite:affiliation>Pennsylvania State University</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Baron, Michael D.</datacite:creatorName>

  
<datacite:givenName>Michael D.</datacite:givenName>

  
<datacite:familyName>Baron</datacite:familyName>

  
<datacite:affiliation>The Pirbright Institute</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Bjørnstad, Ottar N.</datacite:creatorName>

  
<datacite:givenName>Ottar N.</datacite:givenName>

  
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<datacite:affiliation>Pennsylvania State University</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Juleff, Nick</datacite:creatorName>

  
<datacite:givenName>Nick</datacite:givenName>

  
<datacite:familyName>Juleff</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0002-0402-9658</datacite:nameIdentifier>

  
<datacite:affiliation>Bill &amp; Melinda Gates Foundation</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Gebre, Solomon</datacite:creatorName>

  
<datacite:givenName>Solomon</datacite:givenName>

  
<datacite:familyName>Gebre</datacite:familyName>

  
<datacite:affiliation>Animal Health Institute</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Chibssa, Tesfaye Rufael</datacite:creatorName>

  
<datacite:givenName>Tesfaye Rufael</datacite:givenName>

  
<datacite:familyName>Chibssa</datacite:familyName>

  
<datacite:affiliation>Animal Health Institute</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Forza, Mesfin Sahle</datacite:creatorName>

  
<datacite:givenName>Mesfin Sahle</datacite:givenName>

  
<datacite:familyName>Forza</datacite:familyName>

  
<datacite:affiliation>Animal Health Institute</datacite:affiliation>

  
</datacite:creator>

  
<datacite:creator>
  
<datacite:creatorName nameType="Personal">Buza, Joram</datacite:creatorName>

  
<datacite:givenName>Joram</datacite:givenName>

  
<datacite:familyName>Buza</datacite:familyName>

  
<datacite:affiliation>Nelson Mandela African Institution of Science and Technology</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Asgedom, Hagos</datacite:creatorName>

  
<datacite:givenName>Hagos</datacite:givenName>

  
<datacite:familyName>Asgedom</datacite:familyName>

  
<datacite:affiliation>Animal Health Institute</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Hudson, Peter J.</datacite:creatorName>

  
<datacite:givenName>Peter J.</datacite:givenName>

  
<datacite:familyName>Hudson</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0003-0468-3403</datacite:nameIdentifier>

  
<datacite:affiliation>Pennsylvania State University</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Cattadori, Isabella M.</datacite:creatorName>

  
<datacite:givenName>Isabella M.</datacite:givenName>

  
<datacite:familyName>Cattadori</datacite:familyName>

  
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<datacite:affiliation>Pennsylvania State University</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Peters, Andrew R.</datacite:creatorName>

  
<datacite:givenName>Andrew R.</datacite:givenName>

  
<datacite:familyName>Peters</datacite:familyName>

  
<datacite:affiliation>University of Edinburgh</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Bailey, Dalan</datacite:creatorName>

  
<datacite:givenName>Dalan</datacite:givenName>

  
<datacite:familyName>Bailey</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0002-5640-2266</datacite:nameIdentifier>

  
<datacite:affiliation>The Pirbright Institute</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Cleaveland, Sarah</datacite:creatorName>

  
<datacite:givenName>Sarah</datacite:givenName>

  
<datacite:familyName>Cleaveland</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0002-0456-0959</datacite:nameIdentifier>

  
<datacite:affiliation>University of Glasgow</datacite:affiliation>

  
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<datacite:creatorName nameType="Personal">Willett, Brian J.</datacite:creatorName>

  
<datacite:givenName>Brian J.</datacite:givenName>

  
<datacite:familyName>Willett</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0001-8912-3266</datacite:nameIdentifier>

  
<datacite:affiliation>University of Glasgow</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Schulz, Claudia</datacite:creatorName>

  
<datacite:givenName>Claudia</datacite:givenName>

  
<datacite:familyName>Schulz</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0003-4614-618X</datacite:nameIdentifier>

  
<datacite:affiliation>University of Veterinary Medicine Vienna</datacite:affiliation>

  
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<datacite:creatorName nameType="Personal">Kidane, Menbere</datacite:creatorName>

  
<datacite:givenName>Menbere</datacite:givenName>

  
<datacite:familyName>Kidane</datacite:familyName>

  
<datacite:affiliation>Animal Health Institute</datacite:affiliation>

  
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<datacite:creatorName nameType="Personal">Mohammed, Abde Aliy</datacite:creatorName>

  
<datacite:givenName>Abde Aliy</datacite:givenName>

  
<datacite:familyName>Mohammed</datacite:familyName>

  
<datacite:affiliation>Animal Health Institute</datacite:affiliation>

  
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<datacite:creatorName nameType="Personal">Belaineh, Redeat</datacite:creatorName>

  
<datacite:givenName>Redeat</datacite:givenName>

  
<datacite:familyName>Belaineh</datacite:familyName>

  
<datacite:affiliation>Animal Health Institute</datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Shegu, Dereje</datacite:creatorName>

  
<datacite:givenName>Dereje</datacite:givenName>

  
<datacite:familyName>Shegu</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0002-2907-6151</datacite:nameIdentifier>

  
<datacite:affiliation>Animal Health Institute</datacite:affiliation>

  
</datacite:creator>

  
<datacite:creator>
  
<datacite:creatorName nameType="Personal">Aklilu, Fasil</datacite:creatorName>

  
<datacite:givenName>Fasil</datacite:givenName>

  
<datacite:familyName>Aklilu</datacite:familyName>

  
<datacite:nameIdentifier nameIdentifierScheme="ORCID" schemeURI="https://orcid.org/">0000-0001-9846-0301</datacite:nameIdentifier>

  
<datacite:affiliation>Animal Health Institute </datacite:affiliation>

  
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<datacite:creator>
  
<datacite:creatorName nameType="Personal">Sibhatu, Demeke</datacite:creatorName>

  
<datacite:givenName>Demeke</datacite:givenName>

  
<datacite:familyName>Sibhatu</datacite:familyName>

  
<datacite:affiliation>Animal Health Institute</datacite:affiliation>

  
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<dc:publisher>Nature Portfolio</dc:publisher>

  
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<dc:language>eng</dc:language>

  
<dc:description xml:lang="en">Peste des petits ruminants virus (PPRV) is a multi-host pathogen with sheep and goats as main hosts. To investigate the role of cattle in the epidemiology of PPR, we simulated conditions similar to East African zero-grazing husbandry practices in a series of trials with local Zebu cattle (Bos taurus indicus) co-housed with goats (Capra aegagrus hircus). Furthermore, we developed a mathematical model to assess the impact of PPRV-transmission from cattle to goats. Of the 32 cattle intranasally infected with the locally endemic lineage IV strain PPRV/Ethiopia/Habru/2014 none transmitted PPRV to 32 co-housed goats. However, these cattle or cattle co-housed with PPRV-infected goats seroconverted. The results confirm previous studies that cattle currently play a negligible role in PPRV-transmission and small ruminant vaccination is sufficient for eradication. However, the possible emergence of PPRV strains more virulent for cattle may impact eradication. Therefore, continued monitoring of PPRV circulation and evolution is recommended.</dc:description>

  
<datacite:subjects>
  
<datacite:subject xml:lang="en">Animals; Peste-des-Petits-Ruminants transmission virology epidemiology; Cattle; Peste-des-petits-ruminants virus immunology physiology; Goats virology; Goat Diseases virology transmission; Cattle diseases transmission virology epidemiology; Disease eradication methods</datacite:subject>

  
</datacite:subjects>

  
<licenseCondition uri="http://creativecommons.org/licenses/by/4.0/">http://creativecommons.org/licenses/by/4.0/</licenseCondition>

  
<file mimeType="application/pdf" objectType="fulltext">https://phaidra.vetmeduni.ac.at/api/object/o:3531/download</file>

  
<datacite:alternateIdentifiers>
  
<datacite:alternateIdentifier alternateIdentifierType="DOI">10.1038/s42003-024-06619-2</datacite:alternateIdentifier>

  
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<datacite:relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://phaidra.vetmeduni.ac.at/o:605</datacite:relatedIdentifier>

  
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<dc:format>application/pdf</dc:format>

  
<dc:source>Communications Biology 7(1) (2024)</dc:source>

  
<citationTitle>Communications Biology</citationTitle>

  
<citationVolume>7</citationVolume>

  
<citationIssue>1</citationIssue>

  
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<datacite:size>2.06 MB</datacite:size>

  
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<datacite:dates>
  
<datacite:date dateType="Issued">2024</datacite:date>

  
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