https://phaidra.vetmeduni.ac.at/o:3364 European Competence Network on Mastocytosis (ECNM): 20-Year Jubilee, Updates, and Future Perspectives Valent, Peter Peter Valent Medical University of Vienna Arock, Michel Michel Arock Sorbonne Université Triggiani, Massimo Massimo Triggiani University of Salerno Horny, Hans-Peter Hans-Peter Horny Ludwig-Maximilians-Universität München Orfao, Alberto Alberto Orfao Universidad de Salamanca Reiter, Andreas Andreas Reiter University Hospital Mannheim Mayer, Jiri Jiri Mayer University Hospital Brno / Masaryk University Sabato, Vito Vito Sabato University of Antwerp / Antwerp University Hospital Hadzijusufovic, Emir Emir Hadzijusufovic 0000-0001-7409-4204 University of Veterinary Medicine Vienna / Medical University of Vienna Siebenhaar, Frank Frank Siebenhaar Charité - Universitätsmedizin Berlin / Fraunhofer Institute for Translational Medicine and Pharmacology Hägglund, Hans Hans Hägglund Uppsala University Hospital Oude Elberink, Hanneke N. G. Hanneke N. G. Oude Elberink University of Groningen Gülen, Theo Theo Gülen Karolinska University Hospital / Karolinska Institutet Schwaab, Juliana Juliana Schwaab University Hospital Mannheim Grattan, Clive Clive Grattan Guy's Hospital Radia, Deepti Deepti Radia Guy's Hospital Nilsson, Gunnar Gunnar Nilsson Yavuz, Selim Selim Yavuz Istanbul University Varkonyi, Judit Judit Varkonyi Semmelweis University Alvarez-Twose, Ivan Ivan Alvarez-Twose Hospital Virgen del Valle Brockow, Knut Knut Brockow Technical University of Munich Doubek, Michael Michael Doubek University Hospital Brno / Masaryk University Lange, Magdalena Magdalena Lange Gdańsk Medical University Zanotti, Roberta Roberta Zanotti University Hospital of Verona Broesby-Olsen, Sigurd Sigurd Broesby-Olsen Odense University Hospital Nedoszytko, Boguslaw Boguslaw Nedoszytko Gdańsk Medical University Hoermann, Gregor Gregor Hoermann Medical University of Vienna / Munich Leukemia Laboratory (Germany) Sotlar, Karl Karl Sotlar Paracelsus Medical University Kluin-Nelemans, Hanneke C. Hanneke C. Kluin-Nelemans University of Groningen Hermine, Olivier Olivier Hermine Niedoszytko, Marek Marek Niedoszytko Gdańsk Medical University Sperr, Wolfgang R. Wolfgang R. Sperr Medical University of Vienna Hartmann, Karin Karin Hartmann University of Basel / University Hospital of Basel Bonadonna, Patrizia Patrizia Bonadonna Verona University Hospital Elsevier text eng In 2002, the European Competence Network on Mastocytosis (ECNM) was launched as a multidisciplinary collaborative initiative to increase the awareness and to improve diagnosis and management of patients with mast cell (MC) disorders. The ECNM consists of a net of specialized centers, expert physicians, and scientists who dedicate their work to MC diseases. One essential aim of the ECNM is to timely distribute all available information about the disease to patients, doctors, and scientists. In the past 20 years, the ECNM has expanded substantially and contributed successfully to the development of new diagnostic concepts, and to the classification, prognostication, and treatments of patients with mastocytosis and MC activation disorders. The ECNM also organized annual meetings and several working conferences, thereby supporting the development of the World Health Organization classification between 2002 and 2022. In addition, the ECNM established a robust and rapidly expanding patient registry and supported the development of new prognostic scoring systems and new treatment approaches. In all projects, ECNM representatives collaborated closely with their U.S. colleagues, various patient organizations, and other scientific networks. Finally, ECNM members have started several collaborations with industrial partners, leading to the preclinical development and clinical testing of KIT-targeting drugs in systemic mastocytosis, and some of these drugs received licensing approval in recent years. All these networking activities and collaborations have strengthened the ECNM and supported our efforts to increase awareness of MC disorders and to improve diagnosis, prognostication, and therapy in patients. Humans; Mastocytosis Diagnosis Therapy; Mastocytosis, Systemic Diagnosis; Forecasting; Mast Cells http://creativecommons.org/licenses/by/4.0/ https://phaidra.vetmeduni.ac.at/api/object/o:3364/download 10.1016/j.jaip.2023.02.021 https://phaidra.vetmeduni.ac.at/o:605 application/pdf Journal of Allergy and Clinical Immunology - In Practice 11(6), 1706-1717 (2023) Journal of Allergy and Clinical Immunology - In Practice 11 6 1706 1717 622.25 kB 2023