
<ns0:uwmetadata xmlns:ns0="http://phaidra.univie.ac.at/XML/metadata/V1.0" xmlns:ns1="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0" xmlns:ns10="http://phaidra.univie.ac.at/XML/metadata/provenience/V1.0" xmlns:ns11="http://phaidra.univie.ac.at/XML/metadata/provenience/V1.0/entity" xmlns:ns12="http://phaidra.univie.ac.at/XML/metadata/digitalbook/V1.0" xmlns:ns13="http://phaidra.univie.ac.at/XML/metadata/etheses/V1.0" xmlns:ns2="http://phaidra.univie.ac.at/XML/metadata/extended/V1.0" xmlns:ns3="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0/entity" xmlns:ns4="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0/requirement" xmlns:ns5="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0/educational" xmlns:ns6="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0/annotation" xmlns:ns7="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0/classification" xmlns:ns8="http://phaidra.univie.ac.at/XML/metadata/lom/V1.0/organization" xmlns:ns9="http://phaidra.univie.ac.at/XML/metadata/histkult/V1.0">
  <ns1:general>
    <ns1:identifier>o:2977</ns1:identifier>
    <ns1:title language="en">Genome-Wide Association Study Revealed Putative SNPs and Candidate Genes Associated with Growth and Meat Traits in Japanese Quail</ns1:title>
    <ns1:language>en</ns1:language>
    <ns1:description language="en">The search for SNPs and candidate genes that determine the manifestation of major selected traits is one crucial objective for genomic selection aimed at increasing poultry production efficiency. Here, we report a genome-wide association study (GWAS) for traits characterizing meat performance in the domestic quail. A total of 146 males from an F2 reference population resulting from crossing a fast (Japanese) and a slow (Texas White) growing breed were examined. Using the genotyping-by-sequencing technique, genomic data were obtained for 115,743 SNPs (92,618 SNPs after quality control) that were employed in this GWAS. The results identified significant SNPs associated with the following traits at 8 weeks of age: body weight (nine SNPs), daily body weight gain (eight SNPs), dressed weight (33 SNPs), and weights of breast (18 SNPs), thigh (eight SNPs), and drumstick (three SNPs). Also, 12 SNPs and five candidate genes (GNAL, DNAJC6, LEPR, SPAG9, and SLC27A4) shared associations with three or more traits. These findings are consistent with the understanding of the genetic complexity of body weight-related traits in quail. The identified SNPs and genes can be used in effective quail breeding as molecular genetic markers for growth and meat characteristics for the purpose of genetic improvement.</ns1:description>
    <ns1:keyword language="en">Male; Animals; Genome-Wide Association Study; Coturnixgenetics; Polymorphism, Single Nucleotidegenetics; Meatanalysis; Body Weightgenetics</ns1:keyword>
    <ns2:identifiers>
      <ns2:resource>1552099</ns2:resource>
      <ns2:identifier>10.3390/genes15030294</ns2:identifier>
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  <ns1:lifecycle>
    <ns1:upload_date>2024-05-14T08:26:36.402Z</ns1:upload_date>
    <ns1:status>44</ns1:status>
    <ns2:peer_reviewed>yes</ns2:peer_reviewed>
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        <ns3:firstname>Natalia A.</ns3:firstname>
        <ns3:lastname>Volkova</ns3:lastname>
        <ns3:institution>L. K. Ernst Federal Research Center for Animal Husbandry</ns3:institution>
        <ns3:orcid>0000-0001-7191-3550</ns3:orcid>
      </ns1:entity>
      <ns1:entity seq="15">
        <ns3:firstname>Michael N.</ns3:firstname>
        <ns3:lastname>Romanov</ns3:lastname>
        <ns3:institution>L. K. Ernst Federal Research Center for Animal Husbandry / University of Kent</ns3:institution>
        <ns3:type>person</ns3:type>
        <ns3:orcid>0000-0003-3584-4644</ns3:orcid>
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      <ns1:entity seq="16">
        <ns3:firstname>Alexandra S.</ns3:firstname>
        <ns3:lastname>Abdelmanova</ns3:lastname>
        <ns3:institution>L. K. Ernst Federal Research Center for Animal Husbandry</ns3:institution>
        <ns3:type>person</ns3:type>
      </ns1:entity>
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        <ns3:firstname>Polina V.</ns3:firstname>
        <ns3:lastname>Larionova</ns3:lastname>
        <ns3:institution>L. K. Ernst Federal Research Center for Animal Husbandry</ns3:institution>
        <ns3:type>person</ns3:type>
      </ns1:entity>
      <ns1:entity seq="13">
        <ns3:firstname>Nadezhda Yu</ns3:firstname>
        <ns3:lastname>German</ns3:lastname>
        <ns3:institution>L. K. Ernst Federal Research Center for Animal Husbandry</ns3:institution>
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      </ns1:entity>
      <ns1:entity seq="12">
        <ns3:firstname>Anastasia N.</ns3:firstname>
        <ns3:lastname>Vetokh</ns3:lastname>
        <ns3:institution>L. K. Ernst Federal Research Center for Animal Husbandry</ns3:institution>
        <ns3:type>person</ns3:type>
        <ns3:orcid>0000-0002-2865-5960</ns3:orcid>
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      <ns1:entity seq="11">
        <ns3:firstname>Alexey V.</ns3:firstname>
        <ns3:lastname>Shakhin</ns3:lastname>
        <ns3:institution>L. K. Ernst Federal Research Center for Animal Husbandry</ns3:institution>
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        <ns3:firstname>Ludmila A</ns3:firstname>
        <ns3:lastname>Volkova</ns3:lastname>
        <ns3:institution>L. K. Ernst Federal Research Center for Animal Husbandry</ns3:institution>
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        <ns3:firstname>Alexander A.</ns3:firstname>
        <ns3:lastname>Sermyagin</ns3:lastname>
        <ns3:institution>L. K. Ernst Federal Research Center for Animal Husbandry</ns3:institution>
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        <ns3:orcid>0000-0002-1799-6014</ns3:orcid>
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        <ns3:firstname>Dmitry V.</ns3:firstname>
        <ns3:lastname>Anshakov</ns3:lastname>
        <ns3:institution>Russian Academy of Sciences</ns3:institution>
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        <ns3:firstname>Vladimir I.</ns3:firstname>
        <ns3:lastname>Fisinin</ns3:lastname>
        <ns3:institution>Russian Academy of Sciences</ns3:institution>
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        <ns3:firstname>Darren K.</ns3:firstname>
        <ns3:lastname>Griffin</ns3:lastname>
        <ns3:institution>University of Kent</ns3:institution>
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        <ns3:orcid>0000-0001-7595-3226</ns3:orcid>
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        <ns3:firstname>Johann</ns3:firstname>
        <ns3:lastname>Sölkner</ns3:lastname>
        <ns3:institution>University of Natural Resources and Life Sciences Vienna</ns3:institution>
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        <ns3:firstname>Gottfried</ns3:firstname>
        <ns3:lastname>Brem</ns3:lastname>
        <ns3:institution>University of Veterinary Medicine Vienna</ns3:institution>
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        <ns3:orcid>0000-0002-7522-0708</ns3:orcid>
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        <ns3:firstname>John C.</ns3:firstname>
        <ns3:lastname>McEwan</ns3:lastname>
        <ns3:institution>Invermay Agricultural Centre</ns3:institution>
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        <ns3:firstname>Rudiger</ns3:firstname>
        <ns3:lastname>Brauning</ns3:lastname>
        <ns3:institution>Invermay Agricultural Centre</ns3:institution>
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        <ns3:firstname>Natalia A.</ns3:firstname>
        <ns3:lastname>Zinovieva</ns3:lastname>
        <ns3:institution>L. K. Ernst Federal Research Center for Animal Husbandry</ns3:institution>
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  <ns12:digitalbook>
    <ns12:name_magazine language="en">Genes</ns12:name_magazine>
    <ns12:pagination>17</ns12:pagination>
    <ns12:volume>15</ns12:volume>
    <ns12:booklet>3</ns12:booklet>
    <ns12:publisher>MDPI</ns12:publisher>
    <ns12:releaseyear>2024</ns12:releaseyear>
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