phaidra.vetmeduni.ac.at o:2977 DOI 10.3390/genes15030294 Genome-Wide Association Study Revealed Putative SNPs and Candidate Genes Associated with Growth and Meat Traits in Japanese Quail The search for SNPs and candidate genes that determine the manifestation of major selected traits is one crucial objective for genomic selection aimed at increasing poultry production efficiency. Here, we report a genome-wide association study (GWAS) for traits characterizing meat performance in the domestic quail. A total of 146 males from an F2 reference population resulting from crossing a fast (Japanese) and a slow (Texas White) growing breed were examined. Using the genotyping-by-sequencing technique, genomic data were obtained for 115,743 SNPs (92,618 SNPs after quality control) that were employed in this GWAS. The results identified significant SNPs associated with the following traits at 8 weeks of age: body weight (nine SNPs), daily body weight gain (eight SNPs), dressed weight (33 SNPs), and weights of breast (18 SNPs), thigh (eight SNPs), and drumstick (three SNPs). Also, 12 SNPs and five candidate genes (GNAL, DNAJC6, LEPR, SPAG9, and SLC27A4) shared associations with three or more traits. These findings are consistent with the understanding of the genetic complexity of body weight-related traits in quail. The identified SNPs and genes can be used in effective quail breeding as molecular genetic markers for growth and meat characteristics for the purpose of genetic improvement. eng Male; Animals; Genome-Wide Association Study; Coturnixgenetics; Polymorphism, Single Nucleotidegenetics; Meatanalysis; Body Weightgenetics 2024-05-14T08:31:58.700Z LOMv1.0 Author BEGIN:VCARD VERSION:3.0 N:Volkova;Natalia A.; FN:Natalia A. Volkova X-ORCID:https://orcid.org/0000-0001-7191-3550 END:VCARD BEGIN:VCARD VERSION:3.0 N:Zinovieva;Natalia A.; FN:Natalia A. Zinovieva X-ORCID:https://orcid.org/0000-0003-4017-6863 END:VCARD BEGIN:VCARD VERSION:3.0 N:Brauning;Rudiger; FN:Rudiger Brauning END:VCARD BEGIN:VCARD VERSION:3.0 N:McEwan;John C.; FN:John C. McEwan X-ORCID:https://orcid.org/0000-0003-4801-6207 END:VCARD BEGIN:VCARD VERSION:3.0 N:Brem;Gottfried; FN:Gottfried Brem X-ORCID:https://orcid.org/0000-0002-7522-0708 END:VCARD BEGIN:VCARD VERSION:3.0 N:Sölkner;Johann; FN:Johann Sölkner X-ORCID:https://orcid.org/0000-0002-1517-5829 END:VCARD BEGIN:VCARD VERSION:3.0 N:Griffin;Darren K.; FN:Darren K. Griffin X-ORCID:https://orcid.org/0000-0001-7595-3226 END:VCARD BEGIN:VCARD VERSION:3.0 N:Fisinin;Vladimir I.; FN:Vladimir I. Fisinin END:VCARD BEGIN:VCARD VERSION:3.0 N:Anshakov;Dmitry V.; FN:Dmitry V. Anshakov END:VCARD BEGIN:VCARD VERSION:3.0 N:Sermyagin;Alexander A.; FN:Alexander A. Sermyagin X-ORCID:https://orcid.org/0000-0002-1799-6014 END:VCARD BEGIN:VCARD VERSION:3.0 N:Volkova;Ludmila A; FN:Ludmila A Volkova END:VCARD BEGIN:VCARD VERSION:3.0 N:Shakhin;Alexey V.; FN:Alexey V. Shakhin END:VCARD BEGIN:VCARD VERSION:3.0 N:Vetokh;Anastasia N.; FN:Anastasia N. Vetokh X-ORCID:https://orcid.org/0000-0002-2865-5960 END:VCARD BEGIN:VCARD VERSION:3.0 N:German;Nadezhda Yu; FN:Nadezhda Yu German END:VCARD BEGIN:VCARD VERSION:3.0 N:Larionova;Polina V.; FN:Polina V. Larionova END:VCARD BEGIN:VCARD VERSION:3.0 N:Romanov;Michael N.; FN:Michael N. Romanov X-ORCID:https://orcid.org/0000-0003-3584-4644 END:VCARD BEGIN:VCARD VERSION:3.0 N:Abdelmanova;Alexandra S.; FN:Alexandra S. Abdelmanova END:VCARD https://w3id.org/kim/hcrt/scheme https://w3id.org/kim/hcrt/text Textdokument Text LOMv1.0 yes https://creativecommons.org/licenses/by/4.0 application/pdf 3774688 https://phaidra.vetmeduni.ac.at/o:2977 https://phaidra.vetmeduni.ac.at/api/object/o:2977/thumbnail LOMv1.0 discipline