o:2510 Feline Infectious Peritonitis: European Advisory Board on Cat Diseases Guidelines en Feline coronavirus (FCoV) is a ubiquitous RNA virus of cats, which is transmitted faeco-orally. In these guidelines, the European Advisory Board on Cat Diseases (ABCD) presents a comprehensive review of feline infectious peritonitis (FIP). FCoV is primarily an enteric virus and most infections do not cause clinical signs, or result in only enteritis, but a small proportion of FCoV-infected cats develop FIP. The pathology in FIP comprises a perivascular phlebitis that can affect any organ. Cats under two years old are most frequently affected by FIP. Most cats present with fever, anorexia, and weight loss; many have effusions, and some have ocular and/or neurological signs. Making a diagnosis is complex and ABCD FIP Diagnostic Approach Tools are available to aid veterinarians. Sampling an effusion, when present, for cytology, biochemistry, and FCoV RNA or FCoV antigen detection is very useful diagnostically. In the absence of an effusion, fine-needle aspirates from affected organs for cytology and FCoV RNA or FCoV antigen detection are helpful. Definitive diagnosis usually requires histopathology with FCoV antigen detection. Antiviral treatments now enable recovery in many cases from this previously fatal disease; nucleoside analogues (e.g., oral GS-441524) are very effective, although they are not available in all countries. Polymerase-Chain-Reaction; Live Fipv Vaccine; Central-Nervous-System; Direct Immunofluorescence Test; Inhibits Viral Replication; Coronavirus Antibody Titer; Acute-Phase Protein; Quality-Of-Life; Spike Protein; Cerebrospinal-Fluid 1552099 10.3390/v15091847 2024-02-09T10:11:46.146Z 44 yes 46 Séverine Tasker University of Bristol 0000-0002-4059-1402 Diane D. Addie person 0000-0001-7843-2661 Herman Egberink University of Utrecht person 0000-0001-6852-5936 Regina Hofmann-Lehmann University of Zurich person 0000-0001-9750-4296 Margaret J. Hosie University of Glasgow Centre for Virus Research person 0000-0002-4313-5023 Uwe Truyen University of Leipzig person Sándor Belák Swedish University of Agricultural Sciences person 0000-0002-2486-268X Corine Boucraut-Baralon Scanelis Veterinary Test Laboratory person Tadeusz Frymus Warsaw University of Life Sciences person 0000-0002-9160-1455 Albert Lloret Universitat Autònoma de Barcelona person Fulvio Marsilio Università Degli Studi di Teramo person 0000-0001-9552-1199 Maria Grazia Pennisi Università di Messina person 0000-0002-3169-4194 Etienne Thiry Liège University person 0000-0002-9585-7933 Karin Möstl University of Veterinary Medicine Vienna person Katrin Katrin Ludwig Maximilian University Munich person 0000-0002-5256-863X application/pdf 2861795 https://phaidra.vetmeduni.ac.at/o:2510 no yes 16 70 1552253 Viruses 103 15 9 MDPI 2023