https://phaidra.vetmeduni.ac.at/o:2510 Feline Infectious Peritonitis: European Advisory Board on Cat Diseases Guidelines Tasker, Séverine Séverine Tasker 0000-0002-4059-1402 University of Bristol Katrin, Katrin Katrin Katrin 0000-0002-5256-863X Ludwig Maximilian University Munich Möstl, Karin Karin Möstl University of Veterinary Medicine Vienna Thiry, Etienne Etienne Thiry 0000-0002-9585-7933 Liège University Pennisi, Maria Grazia Maria Grazia Pennisi 0000-0002-3169-4194 Università di Messina Marsilio, Fulvio Fulvio Marsilio 0000-0001-9552-1199 Università Degli Studi di Teramo Lloret, Albert Albert Lloret Universitat Autònoma de Barcelona Frymus, Tadeusz Tadeusz Frymus 0000-0002-9160-1455 Warsaw University of Life Sciences Boucraut-Baralon, Corine Corine Boucraut-Baralon Scanelis Veterinary Test Laboratory Belák, Sándor Sándor Belák 0000-0002-2486-268X Swedish University of Agricultural Sciences Truyen, Uwe Uwe Truyen University of Leipzig Hosie, Margaret J. Margaret J. Hosie 0000-0002-4313-5023 University of Glasgow Centre for Virus Research Hofmann-Lehmann, Regina Regina Hofmann-Lehmann 0000-0001-9750-4296 University of Zurich Addie, Diane D. Diane D. Addie 0000-0001-7843-2661 Egberink, Herman Herman Egberink 0000-0001-6852-5936 University of Utrecht MDPI text eng Feline coronavirus (FCoV) is a ubiquitous RNA virus of cats, which is transmitted faeco-orally. In these guidelines, the European Advisory Board on Cat Diseases (ABCD) presents a comprehensive review of feline infectious peritonitis (FIP). FCoV is primarily an enteric virus and most infections do not cause clinical signs, or result in only enteritis, but a small proportion of FCoV-infected cats develop FIP. The pathology in FIP comprises a perivascular phlebitis that can affect any organ. Cats under two years old are most frequently affected by FIP. Most cats present with fever, anorexia, and weight loss; many have effusions, and some have ocular and/or neurological signs. Making a diagnosis is complex and ABCD FIP Diagnostic Approach Tools are available to aid veterinarians. Sampling an effusion, when present, for cytology, biochemistry, and FCoV RNA or FCoV antigen detection is very useful diagnostically. In the absence of an effusion, fine-needle aspirates from affected organs for cytology and FCoV RNA or FCoV antigen detection are helpful. Definitive diagnosis usually requires histopathology with FCoV antigen detection. Antiviral treatments now enable recovery in many cases from this previously fatal disease; nucleoside analogues (e.g., oral GS-441524) are very effective, although they are not available in all countries. Polymerase-Chain-Reaction; Live Fipv Vaccine; Central-Nervous-System; Direct Immunofluorescence Test; Inhibits Viral Replication; Coronavirus Antibody Titer; Acute-Phase Protein; Quality-Of-Life; Spike Protein; Cerebrospinal-Fluid http://creativecommons.org/licenses/by/4.0/ https://phaidra.vetmeduni.ac.at/api/object/o:2510/download 10.3390/v15091847 https://phaidra.vetmeduni.ac.at/o:605 application/pdf Viruses 15(9) (2023) Viruses 15 9 2.73 MB 2023