phaidra.vetmeduni.ac.at o:1981 DOI 10.3390/v14050937 Calicivirus Infection in Cats Feline calicivirus (FCV) is a common pathogen in domestic cats that is highly contagious, resistant to many disinfectants and demonstrates a high genetic variability. FCV infection can lead to serious or even fatal diseases. In this review, the European Advisory Board on Cat Diseases (ABCD), a scientifically independent board of experts in feline medicine from 11 European countries, presents the current knowledge of FCV infection and fills gaps with expert opinions. FCV infections are particularly problematic in multicat environments. FCV-infected cats often show painful erosions in the mouth and mild upper respiratory disease and, particularly in kittens, even fatal pneumonia. However, infection can be associated with chronic gingivostomatitis. Rarely, highly virulent FCV variants can induce severe systemic disease with epizootic spread and high mortality. FCV can best be detected by reverse-transcriptase PCR. However, a negative result does not rule out FCV infection and healthy cats can test positive. All cats should be vaccinated against FCV (core vaccine); however, vaccination protects cats from disease but not from infection. Considering the high variability of FCV, changing to different vaccine strain(s) may be of benefit if disease occurs in fully vaccinated cats. Infection-induced immunity is not life-long and does not protect against all strains; therefore, vaccination of cats that have recovered from caliciviral disease is recommended. eng Recombinant Feline Interferon; Virulent Systemic-Disease; Respiratory-Tract Disease; Quasi-Species Evolution; Chain-Reaction Assay; Capsid Protein; Hypervariable Region; Genetic Diversity; Molecular Characterization; Chronic Gingivostomatitis 2023-08-14T09:14:00.227Z LOMv1.0 Author BEGIN:VCARD VERSION:3.0 N:Hofmann-Lehmann;Regina; FN:Regina Hofmann-Lehmann X-ORCID:https://orcid.org/0000-0001-9750-4296 END:VCARD BEGIN:VCARD VERSION:3.0 N:Möstl;Karin; FN:Karin Möstl END:VCARD BEGIN:VCARD VERSION:3.0 N:Radford;Alan D.; FN:Alan D. Radford END:VCARD BEGIN:VCARD VERSION:3.0 N:Thiry;Etienne; FN:Etienne Thiry X-ORCID:https://orcid.org/0000-0002-9585-7933 END:VCARD BEGIN:VCARD VERSION:3.0 N:Lutz;Hans; FN:Hans Lutz END:VCARD BEGIN:VCARD VERSION:3.0 N:Addie;Diane D.; FN:Diane D. Addie X-ORCID:https://orcid.org/0000-0001-7843-2661 END:VCARD BEGIN:VCARD VERSION:3.0 N:Pennisi;Maria Grazia; FN:Maria Grazia Pennisi END:VCARD BEGIN:VCARD VERSION:3.0 N:Marsilio;Fulvio; FN:Fulvio Marsilio X-ORCID:https://orcid.org/0000-0001-9552-1199 END:VCARD BEGIN:VCARD VERSION:3.0 N:Lloret;Albert; FN:Albert Lloret END:VCARD BEGIN:VCARD VERSION:3.0 N:Frymus;Tadeusz; FN:Tadeusz Frymus X-ORCID:https://orcid.org/0000-0002-9160-1455 END:VCARD BEGIN:VCARD VERSION:3.0 N:Boucraut-Baralon;Corine; FN:Corine Boucraut-Baralon END:VCARD BEGIN:VCARD VERSION:3.0 N:Belák;Sándor; FN:Sándor Belák END:VCARD BEGIN:VCARD VERSION:3.0 N:Tasker;Séverine; FN:Séverine Tasker X-ORCID:https://orcid.org/0000-0002-4059-1402 END:VCARD BEGIN:VCARD VERSION:3.0 N:Truyen;Uwe; FN:Uwe Truyen END:VCARD BEGIN:VCARD VERSION:3.0 N:Egberink;Herman; FN:Herman Egberink X-ORCID:https://orcid.org/0000-0001-6852-5936 END:VCARD BEGIN:VCARD VERSION:3.0 N:Hartmann;Katrin; FN:Katrin Hartmann X-ORCID:https://orcid.org/0000-0002-5256-863X END:VCARD BEGIN:VCARD VERSION:3.0 N:Hosie;Margaret J.; FN:Margaret J. Hosie X-ORCID:https://orcid.org/0000-0002-4313-5023 END:VCARD https://w3id.org/kim/hcrt/scheme https://w3id.org/kim/hcrt/text Textdokument Text LOMv1.0 yes https://creativecommons.org/licenses/by/4.0 application/pdf 921887 https://phaidra.vetmeduni.ac.at/o:1981 https://phaidra.vetmeduni.ac.at/api/object/o:1981/thumbnail LOMv1.0 discipline