phaidra.vetmeduni.ac.at o:1498 DOI 10.1523/ENEURO.0083-22.2022 Validation of a new coil array tailored for dog functional magnetic resonance imaging studies Comparative neuroimaging allows for the identification of similarities and differences between species. It provides an important and promising avenue, to answer questions about the evolutionary origins of the brain´s organization, in terms of both structure and function. Dog functional magnetic resonance imaging (fMRI) has recently become one particularly promising and increasingly used approach to study brain function and coevolution. In dog neuroimaging, image acquisition has so far been mostly performed with coils originally developed for use in human MRI. Since such coils have been tailored to human anatomy, their sensitivity and data quality is likely not optimal for dog MRI. Therefore, we developed a multichannel receive coil (K9 coil, read "canine") tailored for high-resolution functional imaging in canines, optimized for dog cranial anatomy. In this paper we report structural (n = 9) as well as functional imaging data (resting-state, n = 6; simple visual paradigm, n = 9) collected with the K9 coil in comparison to reference data collected with a human knee coil. Our results show that the K9 coil significantly outperforms the human knee coil, improving the signal-to-noise ratio (SNR) across the imaging modalities. We noted increases of roughly 45% signal-to-noise in the structural and functional domain. In terms of translation to fMRI data collected in a visual flickering checkerboard paradigm, group-level analyses show that the K9 coil performs better than the knee coil as well. These findings demonstrate how hardware improvements may be instrumental in driving data quality, and thus, quality of imaging results, for dog-human comparative neuroimaging. eng Canine Neuroimaging Comparative Neuroimaging Dog fMRI Hardware K9 Coil 2023-04-13T14:32:31.703Z LOMv1.0 Author BEGIN:VCARD VERSION:3.0 N:Guran;Catherine-Noémie Alexandrina; FN:Catherine-Noémie Alexandrina Guran END:VCARD BEGIN:VCARD VERSION:3.0 N:Laistler;Elmar; FN:Elmar Laistler END:VCARD BEGIN:VCARD VERSION:3.0 N:Lamm;Claus; FN:Claus Lamm X-ORCID:https://orcid.org/0000-0002-5422-0653 END:VCARD BEGIN:VCARD VERSION:3.0 N:Huber;Ludwig; FN:Ludwig Huber X-ORCID:https://orcid.org/0000-0002-0217-136X END:VCARD BEGIN:VCARD VERSION:3.0 N:Windischberger;Christian; FN:Christian Windischberger END:VCARD BEGIN:VCARD VERSION:3.0 N:Boch;Magdalena; FN:Magdalena Boch END:VCARD BEGIN:VCARD VERSION:3.0 N:Karl;Sabrina; FN:Sabrina Karl X-ORCID:https://orcid.org/0000-0002-7619-728X END:VCARD BEGIN:VCARD VERSION:3.0 N:Sladky;Ronald; FN:Ronald Sladky X-ORCID:https://orcid.org/0000-0002-5986-1572 END:VCARD https://w3id.org/kim/hcrt/scheme https://w3id.org/kim/hcrt/text Textdokument Text LOMv1.0 yes https://creativecommons.org/licenses/by/4.0 application/pdf 1455256 https://phaidra.vetmeduni.ac.at/o:1498 https://phaidra.vetmeduni.ac.at/api/object/o:1498/thumbnail LOMv1.0 discipline